China Factory Direct
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| CAS number | 35661-39-3 |
| Product name | FMOC-Ala-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
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| Pharmaceuticals | Pharmaceutical intermediates | Used as Fmoc-protected amino acids in solid-phase peptide synthesis for manufacturing peptide-based drugs |
| Biochemistry | Peptide synthesis reagent | Applied in solid-phase synthesis to introduce the Fmoc protecting group, preventing side-chain side reactions of amino acids during coupling |
| Organic Synthesis | Protecting group reagent | Employed to prepare Fmoc-protected amino acid derivatives, facilitating subsequent coupling and deprotection steps |
| Materials Science | Intermediate for functional material synthesis | Utilized in synthesizing organic functional materials with defined structures, such as polymers or self-assembling molecules |
| Analytical Chemistry | Reference standard and analytical reagent | Used as a reference standard or derivatization reagent in analytical techniques including high-performance liquid chromatography (HPLC) and mass spectrometry (MS) |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical form (typically white to off-white crystalline powder) to determine if it matches the standard description. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column and a UV detector (e.g., 265 nm or 200–300 nm wavelength). Quantify the main component's purity using peak area normalization or external standard method. |
| Specific Optical Rotation | Polarimetry | Determine the optical rotation of the sample solution in a specified solvent (e.g., DMF or ethanol) and at a defined concentration to verify its chiral configuration matches that of L-alanine. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or digital melting point apparatus to assess the crystallinity and purity of the substance. |
| Water Content | Karl Fischer Titration | Determine the moisture content using volumetric or coulometric Karl Fischer titration to ensure compliance with drying loss or moisture content standards (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Analyze residual organic solvents (e.g., DCM, DMF, ethyl acetate) from synthesis or purification using headspace or direct injection with an FID detector. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure the total content of heavy metals such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmacopoeia or client-specified limits. |
| pH Value (aqueous solution) | pH Meter | Prepare a solution of defined concentration in water and measure its pH to assess acidity/basicity and possible presence of free acid impurities. |
| Thin-Layer Chromatography (TLC) | TLC Plate + Developing Reagent | Rapid screening for impurities or incomplete reaction products. Common developing systems include dichloromethane:methanol (95:5). Detection under UV lamp or by ninhydrin staining. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectrometer (FTIR) | Compare characteristic absorption peaks (e.g., carbonyl ~1700 cm⁻¹, aromatic ring ~1500–1600 cm⁻¹) with standard spectra to confirm structural consistency. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Nuclear Magnetic Resonance Spectrometer | Dissolve the sample in a deuterated solvent (e.g., DMSO-d₆), and verify the molecular structure and purity based on chemical shifts, integration areas, and coupling constants. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 138–142°C |
| Optical Rotation | -20.0 to -17.0° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.