Fmoc-Phe-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35661-40-6 |
| Product name | Fmoc-Phe-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-Phe-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-Phe-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-Phe-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protected amino acid in peptide synthesis for solid-phase or solution-phase peptide chain elongation | Fmoc-based solid-phase peptide synthesis (SPPS), constructing target peptides via iterative deprotection-coupling cycles |
| Biotechnology | Synthesis of fluorescently labeled or multifunctionally modified bioactive peptides | Introduction of side-chain protecting groups under Fmoc strategy to enable selective functionalization |
| Chemical Research | Construction of model peptides or probe molecules containing phenylalanine residues | Amide bond formation using standard peptide coupling reagents (e.g., HBTU, DIC) |
| Pharmaceutical Manufacturing | Production of therapeutic peptide drug intermediates (e.g., GLP-1 analogs, antimicrobial peptides) | Scale-up solid-phase synthesis and purification under GMP conditions |
Manufacturing Quality Control of Fmoc-Phe-OH
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically appears as a white to off-white powder, dry and free of lumps. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase C18 column and UV detector (~254 nm). Purity is calculated by comparing retention time and peak area with a reference standard, typically requiring ≥98% or ≥99%. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs a chiral column to separate L- and D-isomers. Enantiomeric excess (ee value) is evaluated to ensure no residual D-isomer is present. |
| Moisture Content | Karl Fischer Titration | Determines total water content (bound and free water). Controlled within a specified range (e.g., ≤0.5%) to prevent degradation or caking. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents potentially remaining from synthesis (e.g., DMF, methanol, ethyl acetate), in compliance with ICH Q3C limits. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measures residual levels of heavy metals such as lead, mercury, cadmium, and arsenic to ensure compliance with pharmacopeial or customer-specified safety limits. |
| Melting Point | Melting Point Apparatus | Determines the melting temperature range, used as an initial indicator of purity and consistency. The melting point of Fmoc-L-Phe is approximately 196–200°C. |
| Specific Optical Rotation | Polarimetry | Measures specific optical rotation under sodium light (589 nm) at a defined concentration to verify optical activity and consistency with the L-configuration. |
| Infrared Spectrum (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compares characteristic functional group absorption peaks (e.g., amide bond, Fmoc group, benzene ring) with reference spectra to confirm structural identity. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR | Records proton and carbon spectra in deuterated solvents to confirm molecular structure, substitution patterns, and detect impurity signals. Commonly used for batch release or R&D verification. |
Technical Specifications of Fmoc-Phe-OH
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 218-222°C |
| Optical Rotation | -40.0 to -36.0° (c=1, in DMF) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-Phe-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-Phe-OH
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Industrial Fmoc-Phe-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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