China Factory Direct
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| CAS number | 356783-16-9 |
| Product name | 3,6-dichloropyrazine-2-carbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel insecticides and fungicides | Used in nucleophilic substitution reactions between 3,6-dichloropyrazine-2-carbonitrile and amines to construct pyrazine-ring-containing bioactive molecular structures |
| Pharmaceuticals | Synthetic building block for antiviral or antitumor agents | Applied in coupling or cyclization reactions to introduce the pyrazine-2-carbonitrile moiety into drug molecule scaffolds |
| Chemical Reagents | Heterocyclic functionalization reagent for organic synthesis | Acts as an electrophilic substituent or cyanide-activating group in transition metal-catalyzed coupling reactions (e.g., Suzuki, Sonogashira) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on AgCl precipitation potential shift. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to assess inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to derive volume-based particle size distribution in dispersed dry or wet samples. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping to assess powder flow and handling characteristics. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of unknown volatile impurities using gas chromatography coupled with mass spectrometry detection. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 10% w/v in water) using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.