China Factory Direct
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| CAS number | 357263-41-3 |
| Product name | 7-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for small-molecule kinase inhibitors | Used in the synthesis of candidate BTK (Bruton’s tyrosine kinase) inhibitors; the azaindole core is introduced during SAR optimization to enhance target binding affinity and metabolic stability |
| Pharmaceutical R&D | Structural motif for JAK/STAT pathway modulators | Serves as a heterocyclic building block in multistep coupling reactions (e.g., Suzuki or Buchwald–Hartwig cross-coupling) to construct preclinical compounds with selective JAK1 inhibitory activity |
| Agrochemical R&D | Core heterocyclic scaffold for novel insecticide molecular design | Applied in the development of lead compounds targeting insect GABA receptors or nicotinic acetylcholine receptors; hydrophobic substituents are introduced via chlorination-site derivatization to improve membrane penetration |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents based on flame ionization response after gas chromatographic separation. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) via mass spectrometric detection of elemental ions. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride anions using conductivity detection after ion exchange. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by weight difference after high-temperature incineration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting conditions. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in laser light scattering pattern. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.