2,5-Difluorobenzoyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35730-09-7 |
| Product name | 2,5-Difluorobenzoyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,5-Difluorobenzoyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-Difluorobenzoyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-Difluorobenzoyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for fluorinated drug molecules, including antitumor and antiviral agents | Acylation: reacts with amines or alcohols to form corresponding amides or esters |
| Agrochemicals | Synthesis of fluorinated aromatic herbicidal or insecticidal active ingredients | Nucleophilic substitution or coupling reactions: introduces the 2,5-difluorobenzoyl group to enhance biological activity and metabolic stability |
| Liquid Crystal Materials | Liquid crystal monomer or intermediate for high-performance fluorinated liquid crystal compounds | Esterification or condensation reactions: constructs liquid crystal molecular frameworks with tailored dielectric anisotropy and optical properties |
| Organic Synthesis | General acyl chloride reagent for introducing the 2,5-difluorobenzoyl functional group | Classical acylation methods, including Friedel-Crafts acylation and Schotten-Baumann reaction |
Manufacturing Quality Control of 2,5-Difluorobenzoyl chloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic impurities are vaporized in sealed vials and quantified by GC-FID or GC-MS after equilibrium partitioning. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Acid Value | Acid-Base Titration (NaOH standard solution) | Neutralization of acidic impurities (e.g., residual carboxylic acids, HCl) with standardized sodium hydroxide using phenolphthalein indicator. |
| Chloride Content (Inorganic) | Potentiometric Titration (AgNO3 standard solution) | Precipitation of chloride ions as AgCl; endpoint detected by silver ion-selective electrode potential shift. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via ionization in plasma and mass separation; offers sub-ppt detection limits for regulated metals. |
| Residual Benzene | Gas Chromatography (GC) with FID | Separation and quantification using a polar column (e.g., wax-type) and external calibration with benzene reference standard. |
| 2,5-Difluorobenzoic Acid (Hydrolysis Impurity) | HPLC with UV detection | Reverse-phase separation followed by UV absorbance measurement at ~230 nm; quantified against authenticated reference material. |
| Color | Visual Comparison (APHA Scale) | Sample color assessed in a 100-mm cell against platinum-cobalt standard solutions under controlled lighting. |
| Density | Digital Density Meter (Oscillating U-tube) | Measures sample density via resonant frequency shift of a vibrating U-shaped glass tube filled with the liquid. |
| Refractive Index | Digital Refractometer | Determines refractive index by measuring critical angle of total internal reflection at the prism-sample interface. |
| Non-Volatile Residue | Gravimetric Analysis (Evaporation and Weighing) | Sample evaporated to dryness at controlled temperature; residue weighed after cooling in desiccator. |
Technical Specifications of 2,5-Difluorobenzoyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.32–1.34 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,5-Difluorobenzoyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-Difluorobenzoyl chloride
Packaging of 2,5-Difluorobenzoyl chloride
Industrial 2,5-Difluorobenzoyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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