China Factory Direct
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| CAS number | 3581-91-7 |
| Product name | 4,5-Dimethylthiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key side-chain building block for cephalosporin antibiotics (e.g., cefazolin, cefotiam) | Serves as an organic synthesis intermediate to construct drug molecules containing a thiazole ring |
| Agrochemicals | Synthesis of certain high-efficacy, low-toxicity fungicides and insecticides | Incorporated into agrochemical active molecules via chemical modification to enhance biological activity or improve physicochemical properties |
| Organic Synthesis | Specialized intermediate for preparing sulfur- and nitrogen-containing heterocyclic compounds | Undergoes substitution, condensation, and other reactions at the reactive sites of the thiazole ring to synthesize complex organic intermediates |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification relies on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, toluene) by headspace GC with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically or added reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection, calibrated against sodium chloride standards. |
| Sulfate Content | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column with conductivity detection, calibrated against potassium sulfate standards. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube and controlled heating rate per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against white/black background under controlled lighting per EP 2.2.1. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (700–800 C) and weighing; indicates non-volatile inorganic impurities. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral compounds in solution using sodium D-line; confirms enantiomeric identity and purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode and pH meter per USP <791>. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 42–46°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.