China Factory Direct
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| CAS number | 3588-57-6 |
| Product name | N-CARBOBENZOXY-DL-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used in the synthesis of peptide-based drugs as amino acid protecting derivatives |
| Chemical synthesis | Organic synthesis reagent | Applied in organic synthesis as a chiral synthon or catalyst precursor |
| Biotechnology | Peptide/protein research | Applied as N-protected amino acids in solid-phase peptide synthesis (SPPS) |
| Pharmaceutical R&D | Anticancer drug development | Involved in structural modification and optimization of certain antitumor agents |
| Pharmaceuticals | Antiviral drug intermediates | Serves as a key chiral building block in antiviral drug synthesis |
| Pharmaceuticals | CNS drug synthesis | Used in the synthesis of central nervous system agents, including antidepressants and anxiolytics |
| Pharmaceuticals | Enzyme inhibitor synthesis | Applied in the design and synthesis of specific enzyme inhibitors |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Optical Rotation | Polarimetry | Measurement of the angle of rotation of plane-polarized light induced by chiral CBZ-DL-phenylalanine in solution. |
| Loss on Drying | Gravimetric (105 C oven) | Determination of volatile content by measuring mass loss after drying at 105 C to constant weight. |
| Residue on Ignition | Gravimetric (sulfated ash) | Measurement of inorganic residue remaining after controlled ignition at 700-800 C following sulfuric acid treatment. |
| Heavy Metals (as Pb) | Colorimetric (thiourea method) | Visual or spectrophotometric comparison of sample color intensity with lead standards after reaction with thiourea in acidic medium. |
| Chloride Impurity | Argentometric Titration (Mohr method) | Titration with standardized silver nitrate solution; endpoint detected by formation of red-brown silver chromate precipitate. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Formation of barium sulfate precipitate in acidic medium; quantification via turbidity measurement at 420 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., CBZ-glycine, deprotected phenylalanine) using gradient HPLC-UV. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric determination of water based on iodine consumption in pyridine-methanol solvent system. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in a 1% w/v aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration + Culture | Quantitative recovery of viable microorganisms by filtration, followed by growth on nutrient agar under controlled incubation conditions. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +13.5° to +15.5° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.