China Factory Direct
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| CAS number | 360-65-6 |
| Product name | GLYCODEOXYCHOLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for bile acid–based drugs, e.g., ursodeoxycholic acid (UDCA) | Organic synthesis, followed by purification via esterification, hydrolysis, and recrystallization |
| Pharmaceuticals | Adjunctive agent in the treatment of primary biliary cholangitis (PBC) | Formulated in combination with ursodeoxycholic acid to modulate the bile acid profile |
| Cosmetics | Skin conditioning agent and penetration enhancer | Incorporated into topical formulations such as creams and serums to improve transdermal delivery of active ingredients, leveraging its amphiphilic properties |
| Life Sciences Research | Modulator of cell membrane fluidity; tool compound for functional studies of bile acid receptors (TGR5, FXR) | Applied as a specific ligand in in vitro cell culture experiments to treat model cells |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies glycodeoxycholic acid content using reversed-phase HPLC with UV detection at 200-210 nm based on peak area comparison with reference standard. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., deoxycholic acid, glycine, cholic acid) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures residual organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generated electrochemically in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, As, Hg, Cr) after acid digestion using inductively coupled plasma mass spectrometry for multi-element detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature incineration (500-600 C) followed by precise weighing. |
| pH of Solution | Potentiometric Titration | Determines pH of a defined aqueous suspension using a calibrated glass electrode and standardized buffer solutions. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light (589 nm) through a solution in chloroform or methanol to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid-to-liquid phase transition occurs using calibrated capillary tube method per USP <741>. |
| Chloride Content | Ion Chromatography | Quantifies chloride ion impurity using suppressed conductivity detection after separation on an anion-exchange column. |
| Microbial Limits | Membrane Filtration | Detects aerobic mesophilic microorganisms by filtration, membrane transfer to soybean-casein digest agar, and colony enumeration after incubation. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie theory-based light scattering analysis under controlled dispersion conditions. |
| Test Item | Specification |
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| Appearance | White powder |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 175–179°C |
| Optical Rotation | +47.0 to +49.0° (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.