China Factory Direct
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| CAS number | 36082-50-5 |
| Product name | 5-Bromo-2,4-dichloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents, antiviral drugs, and kinase inhibitors | Introduces nitrogen-containing heterocyclic structures via nucleophilic substitution to construct active molecular scaffolds |
| Agrochemicals | Intermediate for synthesizing novel herbicides and fungicides | Participates in coupling or substitution reactions to build bioactive pyrimidine compounds |
| Chemical Research | Organic building block for constructing complex heterocyclic systems | Serves as an arylating reagent in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, physical state, and presence of foreign matter under natural light or standard illumination. The material should typically appear as a white to off-white crystalline powder. |
| Melting Point | Capillary Method or Melting Point Instrument | Determine the melting temperature range using the capillary method or digital melting point instrument. The typical melting point of 5-bromo-2,4-dichloropyrimidine is approximately 70–74 °C, used for purity assessment. |
| Content (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with methanol/water or acetonitrile/water as mobile phase, and UV detector (typically at 254 nm) for quantitative analysis of the main component. Content is calculated using external standard method or area normalization. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same or optimized HPLC conditions as for content determination; used to separate and detect process impurities, degradation products, etc. Typically, individual impurities ≤ 0.5%, total impurities ≤ 1.0%. |
| Water Content | Karl Fischer Titration | Determine moisture content using either volumetric or coulometric Karl Fischer titration. This controls the impact of hygroscopicity on reactions; generally requires water content ≤ 0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection GC with FID detection to analyze residual organic solvents (e.g., dichloromethane, toluene, ethanol) from synthesis processes. Controlled according to ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, determine total or specific heavy metal levels (e.g., lead, cadmium, mercury, arsenic) using AAS or ICP-MS. Typically, total heavy metals ≤ 20 ppm. |
| Residue on Ignition / Ash Content | Gravimetric Method | Ignite the sample at high temperature (e.g., 600–800 °C) to constant weight, then weigh the inorganic residue. Used to assess inorganic impurity levels; generally requires ≤ 0.1%. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.