2-Bromo-4-fluorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 36282-26-5 |
| Product name | 2-Bromo-4-fluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-4-fluorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-4-fluorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-4-fluorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., BTK inhibitors) | Used in nucleophilic substitution or palladium-catalyzed cross-coupling reactions |
| Agrochemical Intermediates | Used to prepare fluorinated benzonitrile-based insecticides and fungicides | Applied in selective bromine substitution or cyano group transformation reactions |
| Organic Synthesis | Starting material for constructing fluorinated aromatic heterocyclic compounds | Employed in metal-catalyzed coupling reactions, such as Suzuki and Heck couplings |
| Materials Science | Functionalized precursor for liquid crystal monomers and organic optoelectronic materials | Processed via hydrolysis of the nitrile group to carboxylic acid or reduction to amine, followed by polymerization |
Manufacturing Quality Control of 2-Bromo-4-fluorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Related Substances (Impurities) | Gas Chromatography (GC) with FID or Mass Spectrometry (GC-MS) | Separation and identification/quantification of structurally related impurities using retention time matching and spectral library correlation (GC-MS) or relative response factors (GC-FID). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile solvent residues are equilibrated in headspace vials, then quantified by GC-FID using calibrated standard solutions per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Sample digested in acid matrix; elemental emission intensities measured at characteristic wavelengths and quantified against multi-element calibration standards. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anionic impurities on an ion-exchange column; chloride quantified via conductivity response relative to calibration standards. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Appearance (Color & Clarity) | Visual Inspection against Standard Solutions (e.g., APHA/Hazen scale) | Comparison of sample solution (in specified solvent, concentration, and path length) to standardized platinum-cobalt color scales under controlled lighting. |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein indicator) | Neutralization of acidic impurities (e.g., residual acids) with standardized sodium hydroxide solution; endpoint determined by color change. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Sample ignited at 700–800 °C after sulfuric acid treatment; non-volatile inorganic residue weighed and expressed as percentage of original sample mass. |
Technical Specifications of 2-Bromo-4-fluorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 62–66°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-4-fluorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-4-fluorobenzonitrile
Packaging of 2-Bromo-4-fluorobenzonitrile
Industrial 2-Bromo-4-fluorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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