China Factory Direct
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| CAS number | 364-75-0 |
| Product name | 2-Fluoro-5-iodonitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Critical intermediates for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Introduces aryl or alkenyl groups via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), or constructs the target molecular scaffold through reduction, diazotization, and related steps |
| Agrochemical Intermediates | Used to prepare novel fluorinated/iodinated heterocyclic insecticides and fungicides | Serves as a polyhalogenated aromatic building block in cyclization, substitution, or metal-catalyzed coupling reactions to construct the pesticidal active core structure |
| Organic Optoelectronic Materials | Building blocks for functional materials in organic light-emitting diode (OLED) hole-transport or electron-transport layers | Converted to conjugated polymers or small-molecule emissive materials via lithium–halogen exchange followed by addition to aldehydes/ketones, or via borylation followed by Suzuki polymerization |
| Liquid Crystal Materials | Used to synthesize fluorinated and iodinated liquid crystal monomers, enhancing dielectric anisotropy and response speed | Undergoes selective nitro reduction to amino followed by diazotization–iodination, or participates directly in nucleophilic substitution or metal-catalyzed coupling to introduce rigid side chains or terminal groups |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., dichloromethane, toluene) by gas chromatography with flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Residual Inorganic Halides (Cl⁻, Br⁻) | Ion Chromatography (IC) | Separation and quantification of halide anions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state and color intensity compared to platinum-cobalt standard solutions. |
| Organic Impurities (Related Substances) | HPLC-UV (with gradient elution) | Identification and quantification of structurally related impurities (e.g., 2-fluoro-5-iodoaniline, nitro reduction by-products) using validated stability-indicating method. |
| Loss on Drying (LOD) | Gravimetric Analysis (105 °C, 2 h) | Mass loss measurement after drying under specified temperature and time to determine volatile and moisture content. |
| Iodine Content | Potentiometric Titration (with AgNO₃) | Quantification of total iodide via argentometric titration monitored by silver ion-selective electrode endpoint detection. |
| Fluorine Content | Combustion Ion Chromatography (CIC) | Oxidative combustion followed by IC analysis of fluoride ions released from C–F bond cleavage. |
| Particle Size Distribution | Laser Diffraction | Size distribution analysis of solid particles in suspension based on angular scattering pattern of laser light. |
| pH of Aqueous Suspension | pH Meter (10% w/v in water) | Measurement of hydrogen ion activity in aqueous slurry using calibrated pH electrode per EP 2.2.3. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 75–79 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.