2',4'-Difluoroacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 364-83-0 |
| Product name | 2',4'-Difluoroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2',4'-Difluoroacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2',4'-Difluoroacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2',4'-Difluoroacetophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidepressant fluoxetine | Used to construct benzodiazepine or tricyclic drug scaffolds via reductive amination, cyclization, and related steps |
| Pesticides | Structural building block for novel fluorinated insecticides and herbicides | Applied as a fluorinated aryl ketone fragment in coupling reactions (e.g., Suzuki, Heck) to introduce bioactive functional groups |
| Materials | Raw material for synthesizing liquid crystal monomers used in liquid crystal displays (LCDs) | Processed via bromination, cyanation, and side-chain modification to produce fluorinated nematic liquid crystal compounds |
| Organic Synthesis | Multifunctional organic synthesis building block for constructing fluorinated heterocycles | Applied in Claisen condensation, Darzens reaction, or cyclization with hydrazine derivatives to prepare fluorinated pyrazoles, triazoles, and other heterocycles |
Manufacturing Quality Control of 2',4'-Difluoroacetophenone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and carrier gas. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities by retention time and UV absorbance relative to the main peak. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvent residues are vaporized in sealed vials and quantified via GC-FID or GC-MS using calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after acid digestion, based on absorption of specific atomic resonance lines. |
| Sulfated Ash | Gravimetric Analysis | Residue mass measured after high-temperature incineration of sample with sulfuric acid followed by ashing at 700 C. |
| Chloride Content | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions eluted from an anion-exchange column. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral compounds in solution at specified wavelength and temperature. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile residue determined after ignition at 800 C following carbonization with sulfuric acid. |
Technical Specifications of 2',4'-Difluoroacetophenone
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light orange clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 41.0 to 43.0 °C |
| Refractive Index (n20/D) | 1.535 to 1.545 |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2',4'-Difluoroacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2',4'-Difluoroacetophenone
Packaging of 2',4'-Difluoroacetophenone
Industrial 2',4'-Difluoroacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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