China Factory Direct
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| CAS number | 36476-86-5 |
| Product name | 1-Benzhydrylazetane-3-carbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antidepressant drugs | As an azetidine derivative, used to construct the core scaffold of active pharmaceutical ingredients for selective serotonin reuptake inhibitors (SSRIs) |
| Organic Synthesis | Cyano- and diphenylmethyl-protected functionalizing reagent | Enables multistep synthesis by converting the cyano group into carboxylic acids, amides, or amines; the diphenylmethyl group provides steric hindrance and stability |
| Fine Chemicals | Raw material for developing novel nitrogen-containing heterocyclic compounds | Applied in constructing biologically active heterocyclic structures for lead compound design in agrochemicals, pharmaceuticals, and functional materials |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or a standard light source. |
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase column (e.g., C18) and a UV detector (based on compound's maximum absorption wavelength ~220–254 nm), determine the content of the target compound using external standard method or area normalization method. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze the structure using ¹H-NMR and ¹³C-NMR to confirm the characteristic peaks of diphenylmethyl, cyano group, and azetidinone ring. |
| Structure Confirmation | Mass Spectrometry (MS, e.g., ESI-MS or EI-MS) | Determine the molecular ion peak ([M+H]+ or M⁺) to verify whether the molecular weight matches the theoretical value (C₁₇H₁₅N₂⁺, theoretical m/z ≈ 247.12). |
| Moisture Content | Karl Fischer Titration | Determine moisture content in the sample by reacting iodine with sulfur dioxide in a pyridine/methanol system; suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | In accordance with ICH Q3C guidelines, detect residual organic solvents used during production (e.g., methanol, ethanol, acetone, dichloromethane), using FID detector. |
| Melting Point | Melting Point Determination (Capillary Method or DSC) | Determine the melting temperature range by heating the sample; it can be used for preliminary assessment of purity and consistency. Differential Scanning Calorimetry (DSC) provides more precise results. |
| Impurity Analysis | HPLC-UV or LC-MS | Separate and identify related substances (e.g., synthetic intermediates, degradation products). Confirm the impurity structures via retention time comparison or mass spectrometry analysis. |
| Cyano Group Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Detect characteristic absorption peaks: ~2200–2260 cm⁻¹ (cyano group — C≡N stretching vibration), combined with other functional group peaks to assist in structural confirmation. |
| Heavy Metal Residue | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect toxic heavy metal elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeia or international standards (e.g., ICH Q3D). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78-82°C |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.