China Factory Direct
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| CAS number | 36520-39-5 |
| Product name | Azetidine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key pharmaceutical intermediate | Serves as a four-membered nitrogen-containing heterocyclic building block for constructing drug molecular scaffolds; participates in ring-opening reactions or functional group transformations to synthesize nitrogen-containing heterocyclic active pharmaceutical ingredients (APIs). |
| Pharmaceutical Chemicals | Homogeneous reaction catalyst | Acts as an organic base or catalytic component in specific organic synthesis reactions to facilitate condensation, addition, and other chemical transformations. |
| Agrochemicals | Agrochemical intermediate | Used to synthesize nitrogen-containing heterocyclic agrochemical compounds with defined biological activity; supports the design and structural modification of agrochemical molecules. |
| Materials Chemistry | Monomer for functional material synthesis | Functions as a functional monomer in ring-opening polymerization and related processes to produce specialty polymers such as polyazetidines or hydrogel materials. |
| Organic Synthesis | Chemical reagent | Serves as a synthetic building block to introduce the azetidine moiety into target molecules, thereby enhancing physicochemical properties such as metabolic stability and aqueous solubility. |
| Test Item | Common Testing Method | Method Summary |
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| Appearance | Visual Inspection | Observe sample color, physical state (e.g., white crystalline or powder), and presence of foreign matter, deliquescence, or caking. |
| Purity/Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column with an appropriate mobile phase to separate the main component; quantify assay using external standard or area normalization method. |
| Related Substances/Impurities | HPLC (Gradient Elution) | Employ gradient elution to separate and detect potential process impurities and degradation products; control impurity levels according to established limits. |
| Water Content | Karl Fischer Titration | Determine trace moisture content by titration to ensure compliance with loss on drying or moisture content specifications. |
| Residual Solvents | Gas Chromatography (GC, Headspace Injection) | Use headspace-GC to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) possibly remaining from synthesis. |
| pH Value | pH Meter (Aqueous Solution) | Prepare a solution of defined concentration and measure its acidity/basicity using a calibrated pH meter to assess stability of hydrochloride salt. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range as a physical constant for identification and preliminary purity assessment. |
| Heavy Metals/Elemental Impurities | ICP-MS or Atomic Absorption Spectroscopy (AAS) | Detect harmful elemental impurities such as lead, cadmium, mercury, and arsenic to comply with ICH Q3D guidelines. |
| Chloride Ion Content | Volumetric Analysis (Argentometry) or Ion Chromatography | Quantify chloride ions via precipitation titration or chromatographic separation to verify structural integrity and stoichiometry of hydrochloride salt. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR) | Confirm molecular structure and functional groups by comparing ¹H-NMR, ¹³C-NMR, and IR spectra with reference standards. |
| Crystal Form (if applicable) | X-Ray Powder Diffraction (XRPD) | Analyze characteristic peaks of crystal structure to control polymorphic forms affecting solubility and stability. |
| Loss on Drying | Oven Drying Method | Dry the sample at a specified temperature until constant weight; calculate mass loss to evaluate volatile substances or adsorbed water content. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.