5,6,7,8-TETRAHYDROISOQUINOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 36556-06-6 |
| Product name | 5,6,7,8-TETRAHYDROISOQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5,6,7,8-TETRAHYDROISOQUINOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5,6,7,8-TETRAHYDROISOQUINOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5,6,7,8-TETRAHYDROISOQUINOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antihypertensive agents (e.g., quinapril precursor), anticancer agents, and neuroprotective compounds | Prepared from β-phenylethylamine and aldehydes/ketones via Pictet–Spengler reaction or catalytic hydrogenation, followed by cyclization, reduction, and other steps to introduce target functional groups |
| Pesticides | Key structural motif in novel insecticides and plant growth regulators | Serves as a chiral azaheterocyclic scaffold in coupling reactions or asymmetric alkylation to construct biologically active heterocyclic derivatives |
| Materials Science | Building block for hole-transport materials in organic light-emitting diodes (OLEDs) and optoelectronic functional molecules | Undergoes bromination and boronic esterification prior to Suzuki coupling, or direct N-alkylation to tune HOMO/LUMO energy levels |
| Fine Chemicals | Chiral catalyst ligands (e.g., THIQ-derived phosphine–nitrogen ligands) and reagents for asymmetric synthesis | Optically pure tetrahydroisoquinoline is obtained via chiral resolution or asymmetric synthesis, followed by N-protection and side-chain functionalization |
Manufacturing Quality Control of 5,6,7,8-TETRAHYDROISOQUINOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies tetrahydroisoquinoline content by retention time and peak area comparison against a certified reference standard. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic impurities by weighing residue after high-temperature ashing at 700-800 C. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals by atomization and absorption measurement at characteristic wavelengths after acid digestion. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Identifies and quantifies structurally related impurities by retention time and UV absorbance relative to main peak. |
| Acid Value | Acid-Base Titration with NaOH | Measures free acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Determines enantiomeric purity by measuring rotation of plane-polarized light at specified wavelength and temperature. |
| Boiling Point | Distillation Method (ASTM D1078) | Determines boiling range using a calibrated distillation apparatus under atmospheric pressure. |
| Density | Digital Density Meter | Measures mass per unit volume at specified temperature using oscillating U-tube principle. |
| pH of Aqueous Solution | pH Meter | Determines hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode system. |
Technical Specifications of 5,6,7,8-TETRAHYDROISOQUINOLINE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.565–1.575 |
| Relative Density (20°C/25°C) | 1.020–1.040 g/cm³ |
| Odor | Characteristic amine-like odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5,6,7,8-TETRAHYDROISOQUINOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5,6,7,8-TETRAHYDROISOQUINOLINE
Safety Information of 5,6,7,8-TETRAHYDROISOQUINOLINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5,6,7,8-TETRAHYDROISOQUINOLINE
Industrial 5,6,7,8-TETRAHYDROISOQUINOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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