China Factory Direct
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| CAS number | 36556-56-6 |
| Product name | 2-CHLORO-4,6-DIFLUOROANILINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for the antifungal agent fluconazole | Serves as the starting material in the synthesis of fluconazole’s active pharmaceutical ingredient via nucleophilic substitution and reduction steps. |
| Agrochemicals | Synthetic intermediate for fluorinated benzoylurea insecticides (e.g., flufenoxuron, diflubenzuron) | Diazotization yields a diazonium salt, followed by reaction with cyanide or Sandmeyer chemistry to introduce key functional groups and construct the benzoylurea scaffold. |
| Fine Chemicals | Structural modification unit for novel fluorinated agrochemical and pharmaceutical molecules | Leverages its halogenated aniline structure—enabling selective fluorine substitution or chlorine transformation—to synthesize functionalized aromatic derivatives. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and detection of impurities (e.g., isomers, residual precursors, dehalogenated products) relative to the main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., toluene, methanol, THF) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in anhydrous methanol-based reagent. |
| Chloride Ion Impurity | Ion Chromatography (IC) | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection for trace-level quantification. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using controlled heating and visual observation of crystal collapse. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter under standardized white light and against a white background. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 C) and subsequent weighing. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via scattering pattern measurement of laser beam passing through dispersed sample in air. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral impurities or enantiomeric excess, using sodium D-line (589 nm) at specified concentration and temperature. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | -15 to -10°C |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.32–1.34 g/cm³ |
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| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.