China Factory Direct
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| CAS number | 36823-88-8 |
| Product name | 4-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for preparing drug molecules containing the 4-(trifluoromethoxy)benzoyl moiety, such as anti-inflammatory, antitumor, or central nervous system agents | Acylation: Reacts with nucleophiles (e.g., amines, alcohols) to form corresponding amides or esters |
| Agrochemicals | Synthesis of biologically active 4-(trifluoromethoxy)benzoyl-based herbicides or insecticides | Nucleophilic substitution or condensation: Constructs the core scaffold of target agrochemical molecules |
| Materials Science | Functional monomer for synthesizing fluorinated high-performance polymers (e.g., liquid crystal materials, optical materials) | Polymerization: Condensation polymerization via the acid chloride group with bifunctional monomers (e.g., diamines, diols) |
| Organic Synthesis | General acylating agent for introducing the 4-(trifluoromethoxy)benzoyl group to modulate lipophilicity, metabolic stability, or electronic properties of molecules | Classical acylation processes, including Friedel–Crafts acylation and Schotten–Baumann reaction |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Acid Value | Acid-Base Titration (NaOH standard solution) | Neutralization of acidic impurities (e.g., residual carboxylic acid) with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after controlled high-temperature ashing at 500-600 C. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after acid digestion, based on absorption of characteristic atomic spectral lines. |
| Chloride Impurity (as Cl-) | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract after sample hydrolysis and dilution. |
| Residual Solvents (e.g., toluene, dichloromethane) | Gas Chromatography (GC) with FID or TCD | Identification and quantification via retention time matching and calibration curve using headspace or direct injection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Determination | Thermal transition measurement using calibrated apparatus; onset and clear point recorded per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or degradation products in solution. |
| Volatile Impurities (Non-specific) | Loss on Drying (LOD) | Gravimetric determination of weight loss after drying under specified temperature and vacuum conditions for fixed duration. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and UV absorbance at 220 nm. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.475–1.485 |
| Relative Density (20°C/25°C) | 1.38–1.42 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.