China Factory Direct
|
|
| CAS number | 36923-17-8 |
| Product name | 7-Amino-3-cephem-4-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Production of cephalosporin antibiotics | Serves as a key intermediate in the chemical synthesis or biosynthetic fermentation of cephalosporin drugs |
| Pharmaceuticals | Synthesis of cefaclor | Produced via substitution and cyclization reactions |
| Pharmaceuticals | Synthesis of cephalexin | Prepared by side-chain introduction and esterification |
| Test Item | Commonly Used Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectrophotometry (IR) | Determine the infrared absorption spectrum of the sample and compare it with the standard spectrum to confirm consistency of characteristic functional group peaks. |
| High-Performance Liquid Chromatography (HPLC) | Identification is performed by comparing the retention time of the sample with that of a reference standard under the same chromatographic conditions. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column and a UV detector (typically at 254 nm or 260 nm), with external or internal standard method to determine the content of the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employs gradient or isocratic elution to separate and quantify process-related impurities and degradation products, such as Δ²-isomer, 7-ACA dimer, etc. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection method using an FID detector to measure residual organic solvents (e.g., acetone, methanol, ethanol) from the manufacturing process. |
| Loss on Drying | Thermogravimetric Analysis / Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105 °C) until constant weight is achieved, then calculate the percentage weight loss to indicate moisture and volatile content. |
| Residue on Ignition (Ash Content) | High-Temperature Ignition Method | Ignite the sample at high temperature (approximately 700–800 °C) and weigh the residue to assess the total inorganic impurity content. |
| pH Value | pH Meter Method | Prepare an aqueous solution of a defined concentration and measure the pH using a calibrated pH meter to ensure compliance with pharmacopoeia specifications. |
| Specific Optical Rotation | Polarimetry | Measure the optical rotation of the aqueous solution at a specific wavelength (usually the sodium D-line, 589 nm) to evaluate optical purity. |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric methods to specifically determine the water content, suitable for thermally unstable samples. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine residual levels of harmful elements such as lead, cadmium, mercury, and arsenic to ensure compliance with specified limits. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -35° to -41° (c=1, in 1N HCl) |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.