Cbz-L-Glutamic acid 1-benzyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3705-42-8 |
| Product name | Cbz-L-Glutamic acid 1-benzyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Cbz-L-Glutamic acid 1-benzyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Cbz-L-Glutamic acid 1-benzyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Cbz-L-Glutamic acid 1-benzyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protected derivative of L-glutamic acid for selective protection of amino and carboxyl groups in peptide synthesis | Used as a building block in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS), with the α-amino group protected by Cbz (benzyloxycarbonyl) and the γ-carboxyl group protected as a benzyl ester to enable subsequent selective deprotection and coupling reactions |
| Organic Synthesis | Chiral synthon or intermediate for constructing complex molecules containing glutamic acid motifs | Selective removal of the benzyl ester or Cbz protecting group under basic or hydrogenation conditions to achieve functional group transformation; commonly employed in asymmetric synthesis and total synthesis of natural products |
| Biochemical Research | Enzymology studies or precursor for probe molecules to investigate glutamate-related metabolism or receptor mechanisms | Converted to free glutamic acid or other derivatives via selective hydrolysis or enzyme-catalyzed reactions for in vitro biochemical assays |
Manufacturing Quality Control of Cbz-L-Glutamic acid 1-benzyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection; baseline separation of L- and D-enantiomers. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) using flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine–methanol–sulfur dioxide medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of heavy metals (Pb, Cd, Hg, As) after acid digestion, using plasma excitation and optical emission detection. |
| Residual Chlorides | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; onset and range reflect crystallinity and purity. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 589 nm, confirming chiral integrity and concentration-corrected enantiomeric identity. |
| Related Substances | HPLC-UV (Gradient) | Detection and quantification of structurally related impurities (e.g., Cbz-L-glutamic acid, dibenzyl ester, hydrolysis/decarboxylation products) using gradient elution. |
| Residue on Ignition | Gravimetric Analysis | Mass loss upon high-temperature ashing (700–800 °C); residue reflects inorganic ash content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against defined standards (e.g., white to off-white crystalline powder). |
Technical Specifications of Cbz-L-Glutamic acid 1-benzyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -26.0 to -22.0° (c=1, in acetic acid) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Cbz-L-Glutamic acid 1-benzyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Cbz-L-Glutamic acid 1-benzyl ester
Safety Information of Cbz-L-Glutamic acid 1-benzyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Cbz-L-Glutamic acid 1-benzyl ester
Industrial Cbz-L-Glutamic acid 1-benzyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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