3-Fluorophenol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 372-20-3 |
| Product name | 3-Fluorophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Fluorophenol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Fluorophenol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Fluorophenol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antifungal agents such as fluconazole and voriconazole | Triazole ring formation via nucleophilic substitution or coupling reactions |
| Agrochemicals | Key intermediate for synthesizing insecticides and fungicides (e.g., flumetramide analogues) | Introduction of fluorinated aryl moieties via nitration, reduction, diazotization, and Sandmeyer reactions |
| Materials | Used to prepare fluorinated liquid crystal monomers and hole-transport materials for organic light-emitting diodes (OLEDs) | Conjugated backbone construction via Ullmann or Suzuki coupling to tune energy levels and thermal stability |
| Dyes | Synthesis of fluorinated azo and anthraquinone dyes with superior lightfastness and weather resistance | Acts as a diazo component in coupling reactions to enhance molecular polarity and color fastness |
Manufacturing Quality Control of 3-Fluorophenol
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase chromatographic column with a UV detector (e.g., 270 nm), employing methanol-water or acetonitrile-water as mobile phases for gradient or isocratic elution to quantitatively analyze the purity of 3-fluorophenol. This method is sensitive and accurate, suitable for quality control of active pharmaceutical ingredients and intermediates. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | After derivatization (e.g., silylation), the sample is injected and separated via gas chromatography, with structural identification of impurities achieved through mass spectrometry. This enables detection and semi-quantification of organic impurities (e.g., isomers, oxidation by-products). Suitable for volatile and semi-volatile impurity analysis. |
| Residual Solvent Detection | Gas Chromatography (GC) | According to ICH guidelines, headspace sampling-GC is employed to detect residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) potentially present during production, ensuring compliance with safety limits. |
| Water Content | Karl Fischer Titration | Based on the quantitative reaction of iodine and sulfur dioxide with water in an anhydrous environment, water content is determined by coulometric or volumetric methods. Suitable for quality control of water-sensitive organic compounds. |
| Melting Point Determination | Capillary Melting Point Method | The sample is loaded into a capillary tube and heated gradually in a melting point apparatus to observe the initial and final melting temperatures. The literature melting point of 3-fluorophenol is approximately 8–10°C (liquid state; note physical state). Melting range narrowness indicates high purity. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to confirm molecular structure by analyzing characteristic chemical shifts (e.g., aromatic protons, coupling patterns of fluorine-adjacent hydrogens) to verify structural correctness. |
| Fluorine Content | Ion Chromatography (IC) or Elemental Analysis | After appropriate sample pretreatment, free fluoride ion content is measured by ion chromatography, or carbon, hydrogen, and fluorine percentages are determined via elemental analysis to validate molecular composition. |
| Appearance and Color | Visual Inspection | Under specified lighting conditions, the sample's color and physical state (typically colorless to pale yellow liquid or low-melting solid) are observed to assess compliance with appearance specifications. |
| Heavy Metal Residue | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After digestion treatment, heavy metals such as lead, cadmium, mercury, and arsenic are detected to ensure compliance with pharmaceutical or industrial safety standards. |
Technical Specifications of 3-Fluorophenol
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.525–1.530 |
| Relative Density (20°C/25°C) | 1.145–1.155 g/cm³ |
| Odor | Characteristic phenolic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Fluorophenol
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NMR Spectra of 3-Fluorophenol
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Industrial 3-Fluorophenol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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