China Factory Direct
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| CAS number | 372-93-0 |
| Product name | 4-FLUORO-1-BUTANOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antitumor agents (e.g., gemcitabine derivatives), antiviral drugs, and fluorinated quinolone antibiotics | Undergoes nucleophilic substitution with amines or structural elaboration via oxidation, esterification, and other steps to construct active molecular frameworks |
| Agrochemical Intermediates | Side-chain modification unit for synthesizing fluorinated insecticides and fungicides (e.g., flumetover derivatives) | Participates in nucleophilic substitution or reacts with isocyanates to generate carbamate prodrugs |
| Electronic Chemicals | Reagent for introducing fluorinated alkoxy side chains into liquid crystal monomers and OLED materials | Constructs high dielectric anisotropy liquid crystal molecules via etherification (e.g., condensation with phenols under basic conditions) |
| Organic Synthesis | Fluorinated alcohol solvent and chiral auxiliary support for asymmetric catalytic reactions | Coordinates to metal catalysts (e.g., Ti, Pd) as a ligand or, after activation, participates in transformations such as epoxidation and cyclopropanation |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies 4-fluoro-1-butanol peak area relative to a calibration curve using an internal or external standard. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between water, iodine, sulfur dioxide, and a base in a methanol-based solvent. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralizes acidic impurities using standardized sodium hydroxide solution and phenolphthalein or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after controlled high-temperature ashing and weighing. |
| Color | Visual Comparison or Hazen (APHA) Scale | Compares sample color against platinum-cobalt standard solutions under controlled lighting conditions. |
| Density at 20 C | Digital Density Meter | Measures mass per unit volume using oscillating U-tube principle with temperature-controlled sample. |
| Refractive Index at 20 C | Refractometry | Determines ratio of light velocity in air vs. sample using critical angle measurement of monochromatic light. |
| Fluoride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separates and quantifies free fluoride ions based on ion exchange and conductivity response. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Measures total heavy metal content after wet digestion by quantifying absorbance of ground-state atoms in flame or graphite furnace. |
| Volatile Impurities (e.g., residual solvents) | Gas Chromatography (GC) with Headspace Sampling | Detects and quantifies low-boiling organic impurities by analyzing vapor phase above equilibrated liquid sample. |
| Chloride Ion Impurity | Potentiometric Titration with AgNO3 | Quantifies chloride via precipitation titration using silver nitrate and silver indicator electrode. |
| Specific Optical Rotation | Polarimetry | Measures angular rotation of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.398–1.402 |
| Relative Density (20°C/25°C) | 0.975–0.985 g/cm³ |
| Odor | Characteristic mild odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.