2,2,2-Trifluoroethylamine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 373-88-6 |
| Product name | 2,2,2-Trifluoroethylamine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,2,2-Trifluoroethylamine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,2,2-Trifluoroethylamine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,2,2-Trifluoroethylamine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of fluorinated pharmaceutical intermediates | Used for nucleophilic substitution and acylation |
| Agrochemicals | Preparation of fluorinated agrochemicals | Used for fluorination and condensation |
| Materials Chemistry | Synthesis of fluorinated polymer monomers | Used for free-radical polymerization and addition reactions |
| Chemical Reagents | Organic synthesis reagent for laboratory use | Used for catalytic hydrogenation and reduction |
| Electronic Chemicals | Etchant additive in semiconductor manufacturing | Used for coordination reactions and surface treatment |
Manufacturing Quality Control of 2,2,2-Trifluoroethylamine hydrochloride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination (Main Component) | High-Performance Liquid Chromatography (HPLC) | Using a C18 chromatographic column, with water-acetonitrile or methanol-buffer salt (e.g., phosphate) as the mobile phase, and a UV detector detecting at wavelengths between 210–230 nm. Quantification of the main component content is performed using external standard or internal standard methods. |
| Content Determination (Main Component) | Non-aqueous Titration | In an acetic acid medium, titrate free amine groups (trifluoroethanamine) with perchloric acid standard solution, using crystal violet or potentiometric method to indicate the endpoint, calculating the hydrochloride content. Suitable for high-purity samples without interfering impurities. |
| Moisture Content | Karl Fischer Titration | Utilizes Karl Fischer reagent composed of iodine, sulfur dioxide, pyridine, and methanol, which reacts quantitatively with water. Moisture is determined by coulometric or volumetric methods, meeting pharmacopoeia requirements (e.g., USP/EP). |
| Chloride Content | Ion Chromatography (IC) | After dissolving the sample in water, chloride ions are separated on an anion exchange column and detected by a conductivity detector. Quantification is achieved by comparing with a standard curve, suitable for trace chloride residue analysis. |
| Chloride Content | Precipitation Titration (Argentometry) | Titrate chloride ions in the sample solution with silver nitrate standard solution, using potassium chromate or potentiometric method to indicate the endpoint, calculating the chloride content. Suitable for rapid screening. |
| Organic Impurities (Related Substances) | High-Performance Liquid Chromatography (HPLC) | Using gradient or isocratic elution, detect possible unreacted raw materials (e.g., trifluoroethanamine, trifluoroethanol) and degradation products (e.g., trifluoroacetic acid). Impurity limits are controlled using area normalization or external standard methods. |
| Solvent Residues | Gas Chromatography (GC) | Using headspace or direct injection, with FID detector, to detect residual solvents such as ethanol, acetone, and acetonitrile. Residual amounts are controlled according to ICH Q3C standards. |
| Melting Point | Melting Point Apparatus | Determine the melting point range of solid samples according to pharmacopoeia methods (typical value: 150–160°C), used for identification and preliminary purity assessment. |
| pH Value (Aqueous Solution) | pH Meter Measurement | Prepare the sample as a specified concentration aqueous solution (e.g., 1% w/v), and measure the pH using a calibrated pH meter. The pH should generally be within the range of 3.5–5.5, reflecting the acidic characteristics of the hydrochloride salt. |
| Appearance and Color | Visual Inspection + Colorimetry | Observe the sample to be white to off-white crystalline powder with no visible foreign matter; when necessary, use a colorimeter (e.g., Hazen units) to quantify the yellowness index and control color consistency. |
| Heavy Metals (Pb, As, etc.) | ICP-MS or Atomic Absorption Spectrometry (AAS) | After sample digestion, determine the content of heavy metals such as lead and arsenic using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or atomic absorption spectrometry. Complies with pharmacopoeia limits (e.g., ≤10 ppm). |
| Particle Size Distribution (If Applicable) | Laser Particle Size Analyzer | For powdered formulations used as raw materials, particle size distribution is measured to ensure flowability and process consistency (e.g., D50 range). |
Technical Specifications of 2,2,2-Trifluoroethylamine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (NMR) |
| Melting Point | 128-132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,2,2-Trifluoroethylamine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,2,2-Trifluoroethylamine hydrochloride
Safety Information of 2,2,2-Trifluoroethylamine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,2,2-Trifluoroethylamine hydrochloride
Industrial 2,2,2-Trifluoroethylamine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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