China Factory Direct
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| CAS number | 37413-91-5 |
| Product name | 3,20-Dioxopregna-1,4,9(11),16-tetraen-21-yl acetate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Steroid hormone intermediate | Used in the synthesis of glucocorticoid drugs |
| Pharmaceuticals | Anti-inflammatory drug synthesis | Serves as a precursor in the preparation of anti-inflammatory agents |
| Pharmaceuticals | Immunosuppressants | Applied in synthetic pathways for immunomodulatory drugs |
| Pharmaceuticals | Endogenous hormone research | Used in studies of steroid metabolism and biological activity |
| Chemical Industry | Organic synthesis reagent | Employed as a starting material in the synthesis of complex steroid molecules |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Structural Confirmation | Nuclear Magnetic Resonance (NMR) | Utilize ¹H-NMR and ¹³C-NMR to analyze chemical shifts and coupling constants of hydrogen and carbon atoms, confirming molecular structural features. |
| Infrared Spectroscopy (IR) | Identify characteristic absorption peaks of functional groups (e.g., carbonyl, hydroxyl, acetate ester), supporting structural elucidation. | |
| Mass Spectrometry (MS) | Determine molecular weight and fragment ions via high-resolution mass spectrometry (HRMS) or LC-MS, verifying molecular formula and structural fragments. | |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase C18 column with UV detector (e.g., 240–254 nm); determine main component purity by area normalization or external standard method. |
| Thin Layer Chromatography (TLC) | Quickly screen for impurities; compare Rf values between sample and reference standard, used for process control or preliminary purity assessment. | |
| Related Substances / Impurity Testing | HPLC Gradient Elution Method | Optimize mobile phase gradient to separate potential process impurities or degradation products; set impurity limits (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Residual Solvents | Gas Chromatography (GC), Headspace Injection | Follow ICH Q3C guidelines; use capillary columns (e.g., DB-624) to detect residual solvents such as methanol, ethyl acetate, and acetone, ensuring compliance with specified limits. |
| Drying Loss | Drying Method / Karl Fischer Water Titration | Drying method (constant weight at 105°C) measures volatile substances; Karl Fischer method precisely determines content of crystalline water or adsorbed water. |
| Residue on Ignition | High-Temperature Ashing (700–800°C) | Determine inorganic salts or metal catalyst residues; control total inorganic impurities (typically ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect residual heavy metals such as lead, arsenic, mercury, and cadmium; comply with pharmacopoeial general chapters (e.g., <20 ppm). |
| Polymorphic Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | For polymorph-sensitive drugs, confirm the dominant crystal form through characteristic diffraction peaks to ensure batch-to-batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range as a physical constant to assist in identification and purity evaluation. |
| Specific Rotation | Polarimeter | Measure optical rotation of a solution at a defined concentration under sodium D-line (589 nm), used for identity confirmation and quality consistency control of chiral compounds. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.