Boc-DL-alanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3744-87-4 |
| Product name | Boc-DL-alanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Boc-DL-alanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-DL-alanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-DL-alanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral building block for the synthesis of peptide-based drugs and intermediates | Employed as a protected amino acid monomer in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS); the BOC group protects the amino functionality, enabling selective deprotection and coupling |
| Biochemical Research | Used to incorporate non-natural amino acids in protein structure and function studies | BOC-DL-alanine is incorporated into peptide chains via chemical synthesis or enzymatic methods to investigate the impact of stereochemical configuration on biological activity |
| Organic Synthesis | Used as a chiral auxiliary or starting material for synthesizing other α-amino acid derivatives | Converted into target compounds through deprotection, alkylation, hydrolysis, and related steps; the DL-configuration is suitable for racemate-related studies or resolution processes |
Manufacturing Quality Control of Boc-DL-alanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantifies BOC-DL-alanine by separation on a reversed-phase column and UV absorbance measurement at ~210 nm, using external standard calibration. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC or Chiral GC | Resolves DL-racemate using a chiral stationary phase; enantiomeric excess calculated from peak area ratio of D- and L-enantiomers. |
| Water Content | Karl Fischer Titration (Coulometric or Volumetric) | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium; quantifies trace water content. |
| Residual Solvents (e.g., THF, DCM, MeOH) | GC-FID or GC-MS | Separates and quantifies volatile organic solvents by gas chromatography with flame ionization or mass-selective detection against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES | Digests sample in acid matrix, then measures elemental concentrations via plasma ionization and mass spectrometry or optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separates chloride anions on an ion-exchange column and detects them based on electrical conductivity relative to chloride standards. |
| Sulfated Ash | Gravimetric Analysis (Ignition at 600–700 °C) | Sample is charred, sulfated with sulfuric acid, and ignited; residual inorganic sulfate ash is weighed after cooling. |
| Specific Optical Rotation | [α]D at 20 °C | Measures rotation of plane-polarized light by chiral compound in solution using a polarimeter; confirms identity and racemic nature (expected near zero for DL-form). |
| pH of Aqueous Solution (1% w/v) | Potentiometric pH Measurement | Determines hydrogen ion activity in aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes scattered laser light intensity patterns from dispersed particles to compute volume-based size distribution. |
| Related Substances (Impurities) | HPLC with UV detection (Gradient method) | Separates and detects structurally related impurities (e.g., BOC-glycine, DL-alanine, di-BOC-alanine) using gradient elution and UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range over which solid transitions to liquid, indicating purity and identity via comparison to reference standard (literature mp: ~75–78 °C). |
Technical Specifications of Boc-DL-alanine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 126-130°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Boc-DL-alanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-DL-alanine
Packaging of Boc-DL-alanine
Industrial Boc-DL-alanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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