China Factory Direct
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| CAS number | 37441-29-5 |
| Product name | 5-Amino-2,4,6- triiodisophthaloyl acid dichloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for non-ionic contrast agents | Serves as a key monomeric raw material; reacts via condensation with side chains (e.g., acetylated amino acid side chains) to synthesize non-ionic X-ray CT contrast agents such as iohexol, iopamidol, and ioversol. |
| Chemical Synthesis | Monomer for functional polymeric materials | Leverages the high reactivity of its amino and acid chloride groups in step-growth polymerization or interfacial polycondensation to produce iodine-containing polyester or polyamide materials for X-ray shielding or biomedical applications. |
| Chemical Synthesis | Organic synthesis reagent | Acts as an acylating agent in organic synthesis reactions, introducing an iodobenzoyl group onto target molecules via its highly reactive acid chloride group to modify molecular polarity or density through incorporation of high-atomic-number iodine. |
| Research | Contrast agent structural modification studies | Used in pharmaceutical R&D laboratories to synthesize novel contrast agent derivatives; structural modifications at the amino or acid chloride terminus optimize osmolality, viscosity, and biocompatibility. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., acetone, dichloromethane) against external standards. |
| Moisture Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent to determine water content via stoichiometric reaction with pyridine/methanol buffer. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Cr after acid digestion, using plasma emission spectroscopy with internal standard correction. |
| Chloride Content | Potentiometric Titration | Titration with standardized silver nitrate solution using silver indicator electrode to detect endpoint based on AgCl precipitation potential shift. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating rate per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering principles to calculate D10, D50, D90 values per ISO 13320. |
| Bulk Density | ASTM D1895 Method A | Measurement of mass per unit volume for freely settled powder in a graduated cylinder under standardized tapping conditions. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing (600-800 C) of sample in platinum crucible. |
| Microbial Limits | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms from dissolved sample using sterile membrane filtration and TSA agar incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 245°C - 250°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.