China Factory Direct
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| CAS number | 374537-97-0 |
| Product name | 2-AMINO-5-BROMO-3,4-DIMETHYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as lead compounds or key intermediates in the synthesis of antitumor, antibacterial, or central nervous system drugs | Multi-step organic synthesis, commonly involving halogen exchange, coupling, or cyclization reactions |
| Agrochemical Intermediates | Serve as synthetic precursors for pyridine-containing insecticides or fungicides | Halogenated pyridine derivatives undergo nucleophilic substitution or metal-catalyzed cross-coupling |
| Organic Synthesis Reagents | Employed to construct complex heterocyclic molecular frameworks, such as polysubstituted pyridine derivatives | Bromine atom enables transition-metal-catalyzed coupling reactions, including Suzuki and Buchwald-Hartwig couplings |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural light or standard illumination. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC (e.g., C18 column) with gradient elution using water and organic solvents (such as methanol or acetonitrile), detected by UV detector (typically around 254 nm). The main component content is calculated using peak area normalization or external standard method. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H NMR and ¹³C NMR to confirm compound structure by comparing chemical shifts and coupling constants with literature values. |
| Structural Confirmation | Mass Spectrometry (MS) | Utilize electrospray ionization (ESI) or electron impact ionization (EI-MS) to determine molecular ion peaks, confirm molecular weight, and analyze fragment ions for structural verification. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH Q3C guidelines to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) from production processes. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration method for precise determination of moisture content; suitable for trace-level water analysis. |
| Melting Point | Melting Point Determination | Determine initial and final melting temperatures using a melting point apparatus or capillary tube method, and compare with literature values to assess purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect heavy metal residues such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopeial or regulatory limits. |
| Related Substances (Impurities) | HPLC Method | Use HPLC to detect potential synthesis intermediates, by-products, or degradation products. Gradient elution is employed for separation, followed by quantification of each impurity peak. |
| Content Determination | HPLC External Standard Method or Titration | Establish a calibration curve using reference standards of known concentration to accurately determine the main component content via HPLC; alternatively, acid-base titration may be used based on amine functionality. |
| Test Item | Specification |
|---|---|
| Appearance | White to yellow to brown crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.