2-(Chloromethyl)quinoline hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3747-74-8 |
| Product name | 2-(Chloromethyl)quinoline hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(Chloromethyl)quinoline hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(Chloromethyl)quinoline hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(Chloromethyl)quinoline hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antimalarial drugs (e.g., chloroquine, hydroxychloroquine) | Used to construct the quinoline side-chain structure via condensation with amines |
| Pesticides | Used in the synthesis of quinoline-containing insecticides or fungicides | Applied in nucleophilic substitution reactions to introduce functional groups that enhance biological activity |
| Organic Synthesis | Alkylating agent for quinoline derivatives | Reacted with nucleophiles under basic conditions to form C–N or C–C bonds |
| Dyes | Used to synthesize quinoline-based dyes or fluorescent probe molecules | Applied in quaternization or condensation reactions to incorporate chromophores or fluorophores |
Manufacturing Quality Control of 2-(Chloromethyl)quinoline hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, dichloromethane) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using plasma emission spectroscopy against matrix-matched calibration curves. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on AgCl precipitation potential change. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after cooling in a desiccator. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution, indicating chiral purity and identity confirmation. |
| pH of Aqueous Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to derive D10, D50, D90 values per ISO 13320. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic bacteria, yeasts, and molds using membrane filtration followed by incubation on appropriate agar media. |
Technical Specifications of 2-(Chloromethyl)quinoline hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow or light orange crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C (decomposes) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(Chloromethyl)quinoline hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(Chloromethyl)quinoline hydrochloride
Safety Information of 2-(Chloromethyl)quinoline hydrochloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-(Chloromethyl)quinoline hydrochloride
Industrial 2-(Chloromethyl)quinoline hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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