5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 374930-88-8 |
| Product name | 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for piperazine derivatives used in the synthesis of active pharmaceutical ingredients (APIs) | Used in organic synthesis |
| Pharmaceuticals | Synthetic building block for antiviral agents (e.g., anti-HIV drugs) | Applied in coupling and substitution reactions |
| Pharmaceuticals | Research and synthesis of anticancer agents | Employed in multi-step organic synthesis |
| Chemicals | Key intermediate for synthesizing complex heterocyclic compounds | Utilized in functional group protection and deprotection |
Manufacturing Quality Control of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, THF, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pd, Ni, Fe) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Residual Palladium | ICP-OES | After microwave-assisted nitric/hydrochloric acid digestion, palladium is measured by inductively coupled plasma optical emission spectroscopy. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion and measurement of particle size distribution based on angular scattering intensity of laser light. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition temperature range using calibrated capillary method per USP <741>. |
| Loss on Drying | Gravimetric Heating | Weight loss measured after drying under controlled temperature and vacuum, indicating volatile content including residual solvents and moisture. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determined in a defined suspension (e.g., 10 mg/mL in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
Safety Information of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE
Industrial 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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