Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 376608-74-1 |
| Product name | Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 376608-74-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 376608-74-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 376608-74-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Antiviral drug intermediate | Used in the synthesis of the antiviral drug sofosbuvir |
| Chemical R&D | Laboratory research and development | Synthesis of novel nucleoside analogs |
| Pharmaceutical Manufacturing | Active pharmaceutical ingredient (API) synthesis | Serves as a key intermediate in coupling reactions |
Manufacturing Quality Control of 376608-74-1
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound using reverse-phase HPLC with UV detection at specified wavelength based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration using iodine-based redox reaction in anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of chiral compound in solution using sodium D-line light to confirm stereochemical integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser beam. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines acidity/basicity of a standardized suspension using calibrated pH electrode and buffer references. |
Technical Specifications of 376608-74-1
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -12° to -16° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 376608-74-1
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 376608-74-1
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Industrial 376608-74-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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