China Factory Direct
|
|
| CAS number | 3770-50-1 |
| Product name | Ethyl indole-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used to construct indole-containing drug molecules via amidation of ethyl indole-2-carboxylate with amine compounds |
| Pharmaceuticals | Synthesis of analgesic and psychotropic drug intermediates | Applied as a key structural unit in cyclization, reduction, or alkylation reactions to build indole-based alkaloid analogues |
| Agrochemicals | Synthesis of novel insecticide and fungicide intermediates | Condensed with heterocyclic amines or thioamide reagents to form biologically active indole derivatives |
| Chemical Manufacturing | Synthesis of fluorescent dyes and organic luminescent materials | Employed as the indole core scaffold, with conjugated systems introduced via Friedel–Crafts alkylation or oxidative coupling reactions |
| Chemical Manufacturing | Chiral building block in organic synthesis | Processed via asymmetric reduction or enzymatic resolution to obtain chiral ethyl indole-2-carboxylate derivatives for complex molecule synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., ethanol, toluene) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Digestion followed by multi-element quantification using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 600-700 C followed by weighing of non-volatile residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of color and clarity against water-white standard in solution or neat state under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light in solution to detect chiral impurities or enantiomeric excess. |
| pH of Aqueous Solution | pH Meter | Measurement of pH in a saturated aqueous suspension or 1% w/v solution using calibrated pH electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after ignition at 700-800 C, per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 124–128°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.