(R)-3-AMINOBUTYRIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3775-73-3 |
| Product name | (R)-3-AMINOBUTYRIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-3-AMINOBUTYRIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-3-AMINOBUTYRIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-3-AMINOBUTYRIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of the antiepileptic drug brivaracetam | Used as a chiral building block in asymmetric synthesis to construct the target molecule’s stereocenter |
| Chemical Research | Chiral synthetic building block | Applied in organic synthesis to construct compounds with defined stereochemistry, participating in coupling, acylation, and related reactions |
| Biopharmaceuticals | Neurotransmitter analog research | Used in neuroscience research to investigate structure–function relationships of γ-aminobutyric acid (GABA) receptors |
Manufacturing Quality Control of (R)-3-AMINOBUTYRIC ACID
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Using reverse-phase or ion-exchange chromatographic columns, combined with UV or evaporative light scattering detectors, to quantitatively analyze the main component content and impurity peak areas, evaluating chemical purity. |
| Enantiomeric Purity (Optical Purity) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Using chiral stationary phase columns to separate (R)- and (S)-enantiomers, calculating enantiomeric excess (e.e.%) via peak area ratio, ensuring stereochemical purity. |
| Moisture Content | Karl Fischer Titration | Utilizing the quantitative reaction between iodine and sulfur dioxide in a pyridine/methanol system with water, determining moisture content through potentiometric titration, complying with pharmacopoeia requirements. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection methods with FID detector to analyze residual organic solvents (e.g., methanol, ethanol, ethyl acetate), meeting ICH Q3C standards. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | Determining the content of elements such as lead, arsenic, mercury, and cadmium after acid digestion of the sample, assessing compliance with pharmacopoeia or ICH Q3D limits. |
| Ignition Residue | Gravimetric Method (High-Temperature Ashing) | Heating the sample in a muffle furnace at 600–800°C until constant weight, weighing the remaining inorganic material to reflect total inorganic impurities. |
| pH Value | pH Meter Measurement | Preparing a certain concentration aqueous solution (e.g., 1% w/v) of the sample and measuring its acidity or alkalinity using a calibrated pH meter, assessing process stability. |
| Specific Rotation | Polarimeter Measurement | Determining the optical rotation of the sample solution under specified wavelength (usually 589 nm, sodium D line) and temperature, calculating specific rotation [α] to verify chiral configuration consistency. |
| Appearance and Characteristics | Visual Inspection and Physical Testing | Observing color, crystal form, odor, solubility, and other physical properties to confirm whether they meet the description of the reference standard, serving as an initial quality judgment basis. |
| Related Substances (Impurity Profile) | Gradient Elution HPLC | Using gradient elution programs to separate and quantify known and unknown impurities, combining with mass spectrometry (LC-MS) for structural confirmation, controlling degradation products and synthetic by-products. |
Technical Specifications of (R)-3-AMINOBUTYRIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% |
| Optical Rotation | -32.0 to -30.0 deg (c=1, H2O) |
| Melting Point | 198 to 202 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-3-AMINOBUTYRIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-3-AMINOBUTYRIC ACID
Packaging of (R)-3-AMINOBUTYRIC ACID
Industrial (R)-3-AMINOBUTYRIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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