2,4-Difluorobiphenyl Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 37847-52-2 |
| Product name | 2,4-Difluorobiphenyl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeElectronic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Difluorobiphenyl
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Difluorobiphenyl Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Difluorobiphenyl
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of fluorinated pesticide intermediates | Used as a key aromatic intermediate in nucleophilic substitution or coupling reactions for synthesizing insecticides such as fipronil |
| Pharmaceuticals | Synthesis of antiviral or antitumor drug intermediates | Applied in constructing complex aromatic ring systems via Suzuki or Ullmann coupling reactions for drug scaffold modification |
| Electronic Materials | Synthesis of liquid crystal display (LCD) monomers | Used as a precursor to fluorinated biphenyl-based liquid crystal compounds; polar groups are introduced via esterification or etherification to adjust dielectric anisotropy |
| High-Performance Polymers | Synthesis of high-performance engineering plastics or polymer monomers | Applied as a fluorinated aromatic monomer in condensation polymerization reactions for polyimides or polyetherketones, enhancing thermal stability and chemical resistance |
Manufacturing Quality Control of 2,4-Difluorobiphenyl
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (typically around 254 nm). Quantitation is performed by peak area normalization or external standard method to evaluate the content of the main component, 2,4-difluorobiphenyl, and impurity levels. |
| Related Substances / Impurity Analysis | Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) | GC is suitable for detecting volatile impurities, commonly using a DB-5 or similar capillary column with an FID detector. HPLC is used for non-volatile or thermally unstable impurities, employing gradient elution to separate and quantify individual impurities, ensuring the product meets quality specifications. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Uses headspace sampling to vaporize residual organic solvents (e.g., toluene, dichloromethane) from the sample before introduction into the GC system. Detection and quantification are performed using FID or MS detectors, in compliance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Employs volumetric or coulometric Karl Fischer titration, offering high specificity and sensitivity for accurate determination of trace moisture in 2,4-difluorobiphenyl. This is critical for product quality and stability control. |
| Melting Point Determination | Capillary Melting Point Method | The sample is packed into a melting point capillary tube and heated at a controlled rate to observe the initial and final melting temperatures. This serves as an auxiliary indicator for assessing compound purity and crystalline form consistency. |
| Elemental Impurities (e.g., Heavy Metals) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After acid digestion of the sample, elemental impurities such as lead, cadmium, mercury, and arsenic are measured using ICP-MS or AAS to ensure compliance with ICH Q3D guidelines for elemental impurities. |
| Structural Confirmation | Proton Nuclear Magnetic Resonance (¹H NMR), Mass Spectrometry (MS), Infrared Spectroscopy (IR) | Combines NMR (to confirm hydrogen environments and substitution patterns), MS (to determine molecular weight and fragmentation patterns), and IR (to identify characteristic functional group absorptions) to verify the correct chemical structure of 2,4-difluorobiphenyl. |
Technical Specifications of 2,4-Difluorobiphenyl
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder or lumps |
| Purity | >=98.0% (by GC-MS) |
| Total Impurities | <=2.0% (by GC-MS) |
| Single Impurity | <=0.5% (by GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 58–62°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Difluorobiphenyl
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Difluorobiphenyl
Packaging of 2,4-Difluorobiphenyl
Industrial 2,4-Difluorobiphenyl Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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