China Factory Direct
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| CAS number | 3789-59-1 |
| Product name | (S)-(-)-1-Amino-1-phenylpropane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral drug intermediates for synthesizing levomethamphetamine-based central nervous system agents (e.g., norpseudoephedrine, certain antidepressants) | Chiral resolution or asymmetric synthesis, commonly employing enzymatic kinetic resolution or chiral chromatographic separation |
| Organic Synthesis | Chiral auxiliaries or ligand precursors for catalysts, used in constructing chiral centers | Applied in asymmetric reactions such as hydroboration-oxidation and epoxidation, serving as chiral induction reagents |
| Analytical Chemistry | Chiral reference standards for method development and validation on chiral columns in gas chromatography (GC) or high-performance liquid chromatography (HPLC) | Dissolved directly to prepare standard solutions, followed by separation and analysis using chiral stationary phase columns (e.g., Chiralcel OD-H, Chiralpak AD) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification of (S)-(-)-1-phenylpropylamine enantioselectively using a chiral stationary phase and UV detection. |
| Enantiomeric Excess (ee) | Chiral GC or Chiral HPLC | Direct comparison of peak areas of (S) and (R) enantiomers to calculate enantiomeric excess. |
| Residual Solvents | Gas Chromatography (GC) with FID | Quantitative determination of volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in pyridine-methanol medium. |
| Heavy Metals | ICP-OES | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using conductivity detection after suppressed elution. |
| Related Substances | HPLC with UV Detection | Detection and quantification of structurally related impurities using reversed-phase chromatography and UV absorbance. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in 1% w/v aqueous solution using calibrated glass electrode. |
| Specific Optical Rotation | [a]D Measurement | Measurement of rotation angle of plane-polarized light at 589 nm to confirm chiral identity and enantiopurity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary method. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature incineration of sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Optical Rotation | -23.0° to -25.5° (c=1, in methanol) |
| Melting Point | 178°C to 182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.