China Factory Direct
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| CAS number | 37942-01-1 |
| Product name | 5-Bromo-2-methoxyphenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antifungal agents (e.g., butenafine analogues) | Two-step bromination-methylation process, starting from 2-methoxyphenol via selective bromination |
| Agrochemical Intermediates | Structural building block for synthesizing novel fungicides and insecticides | Nucleophilic substitution with amines or thiols to construct bromo-methoxyphenyl-containing active molecules |
| Organic Synthesis | Multifunctional aromatic building block for cross-coupling reactions, including Suzuki coupling and Ullmann reactions | Suzuki coupling with arylboronic acids under palladium catalysis; or Ullmann condensation with aryl iodides under copper catalysis |
| Test Item | Common Test Method | Method Overview |
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| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (typically at 254 nm). Effectively separates 5-bromo-2-methoxyphenol from impurities with accurate quantification; suitable for content determination in both active pharmaceutical ingredients and formulations. |
| Structural Confirmation | Liquid Chromatography-Mass Spectrometry (LC-MS) | After separation by LC, mass spectrometry analysis is performed using electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI), providing molecular weight information (e.g., [M+H]⁺ m/z ≈ 200), used for structural confirmation and impurity identification. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Suitable for detection of volatile impurities. The sample is derivatized (e.g., silylation), separated on a capillary column, and detected by mass spectrometry, enabling identification of trace by-products or residual solvents. |
| Assay | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Quantification based on the compound's characteristic absorption peak at a specific wavelength (e.g., 270–280 nm) using a calibration curve. Simple to operate, but susceptible to interference from coexisting substances; conditions must be carefully selected. |
| Residual Solvent Testing | Gas Chromatography with Flame Ionization or Mass Spectrometric Detection (GC-FID/MS) | In accordance with Chinese Pharmacopoeia or ICH Q3A/B guidelines, residual organic solvents (e.g., ethanol, acetone, dichloromethane) from manufacturing processes are detected using headspace or direct injection methods. |
| Moisture Content | Karl Fischer Titration | Determines water content in samples, especially suitable for products sensitive to moisture. Offers high sensitivity and accuracy, and is the standard method for moisture control in pharmaceuticals. |
| Melting Point Determination | Micro Melting Point Apparatus | Determines the melting temperature range (e.g., approximately 105–108 °C) by observing the melting process, aiding in assessing purity and structural consistency; commonly used as a preliminary quality check. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 58–62°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.