2-Chloro-6-hydroxynicotinic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 38025-90-0 |
| Product name | 2-Chloro-6-hydroxynicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 2-Chloro-6-hydroxynicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-6-hydroxynicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-6-hydroxynicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pesticides | Used as a herbicide intermediate, particularly as a key precursor in the synthesis of sulfonylurea herbicides (e.g., halosulfuron-methyl) | Participates in active ingredient construction via nucleophilic substitution, condensation, or coupling reactions |
| Pharmaceuticals | Serves as a pharmaceutical synthetic intermediate for preparing biologically active heterocyclic compounds | Involved in multistep organic synthesis, including amidation, esterification, or metal-catalyzed coupling reactions |
| Fine Chemicals | Used to synthesize other functional nicotinic acid derivatives or ligands | Acts as a building block to introduce the chlorohydroxypyridine moiety in custom molecule synthesis |
Manufacturing Quality Control of 2-Chloro-6-hydroxynicotinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of residual inorganic salts as sulfate ash. |
| pH of Aqueous Suspension | Potentiometric Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using standardized capillary method per USP <741>. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C for 2 hours, indicating volatile content including residual moisture and solvents. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed phase using Mie scattering theory and laser diffraction instrumentation. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to assess chiral purity and identity confirmation. |
Technical Specifications of 2-Chloro-6-hydroxynicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Light-gray solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 2-Chloro-6-hydroxynicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-6-hydroxynicotinic acid
Safety Information of 2-Chloro-6-hydroxynicotinic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Chloro-6-hydroxynicotinic acid
Industrial 2-Chloro-6-hydroxynicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply