China Factory Direct
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| CAS number | 380430-49-9 |
| Product name | (4-BOC-AMINOPHENYL)BORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used to synthesize specific structural motifs in drug molecules, such as those in anticancer and cardiovascular agents. |
| Medical Research | Biomarker | Applied in the study of specific biological processes in cells and tissues. |
| Materials Science | Novel Material Synthesis | Employed as a precursor for synthesizing organic–inorganic hybrid materials with tailored properties. |
| Organic Synthesis | Coupling Reactions | Acts as a nucleophile in Suzuki coupling reactions, enabling cross-coupling with aryl or alkyl halides. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., deboronated, deprotected, or dimeric species) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pd, Ni, Fe) using inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Measures palladium from Suzuki coupling catalyst residues via inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual BOC Protecting Group | 1H NMR | Confirms presence/absence of tert-butoxycarbonyl group by integration of characteristic t-butyl singlet (~1.4 ppm) relative to aromatic protons. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity against established reference standard under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder mode using Mie scattering theory and calibrated instrument. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 60 C under vacuum for 2 hours. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 182-186°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.