METHYL 5-BROMO-6-HYDROXYNICOTINATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 381247-99-0 |
| Product name | METHYL 5-BROMO-6-HYDROXYNICOTINATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYL 5-BROMO-6-HYDROXYNICOTINATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL 5-BROMO-6-HYDROXYNICOTINATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYL 5-BROMO-6-HYDROXYNICOTINATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used in the synthesis of pharmaceutical intermediates exhibiting antibacterial and antiviral activity |
| Chemical Industry | Synthetic Reagent | Serves as a key reagent in organic synthesis for constructing diverse complex molecules |
| Biochemistry | Biologically Active Compound Research | Applied in the design and synthesis of small-molecule compounds associated with specific biological activities |
| Materials Science | Functional Material Synthesis | Employed as a critical intermediate in the synthesis of functional polymers or organic optoelectronic materials |
Manufacturing Quality Control of METHYL 5-BROMO-6-HYDROXYNICOTINATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-methanol buffer; water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for high sensitivity and multi-element capability. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride quantified via calibration curve. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after controlled incineration at 700-800 C; residue weighed following cooling in a desiccator. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature at which solid-to-liquid phase change occurs under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; indicative of chiral purity and enantiomeric excess. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using a calibrated glass electrode and reference electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns from dispersed particles to calculate size distribution based on Mie or Fraunhofer theory. |
| Bulk and Tapped Density | Carr Index Method | Determination of powder flow properties by measuring volume before and after standardized mechanical tapping; densities calculated from mass and volume. |
Technical Specifications of METHYL 5-BROMO-6-HYDROXYNICOTINATE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYL 5-BROMO-6-HYDROXYNICOTINATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYL 5-BROMO-6-HYDROXYNICOTINATE
Safety Information of METHYL 5-BROMO-6-HYDROXYNICOTINATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of METHYL 5-BROMO-6-HYDROXYNICOTINATE
Industrial METHYL 5-BROMO-6-HYDROXYNICOTINATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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