7,8-Dihydroxyflavone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 38183-03-8 |
| Product name | 7,8-Dihydroxyflavone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7,8-Dihydroxyflavone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7,8-Dihydroxyflavone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7,8-Dihydroxyflavone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Neuroprotective agent and TrkB receptor agonist for research on neurological disorders including Alzheimer’s disease, Parkinson’s disease, and depression | Administration in in vitro cell assays (e.g., PC12 cells, primary cortical neurons) and animal models (mice, rats); typically delivered via intraperitoneal injection or oral gavage, with concentration/dose optimized per pharmacodynamic studies |
| Biomedical Research | Molecular probe for inducing synaptic plasticity and activating the brain-derived neurotrophic factor (BDNF) signaling pathway | Dissolved in DMSO to prepare stock solutions, then diluted to final concentrations (typically 0.1–10 μM) for treatment in neuronal culture systems; mechanism validated using techniques including Western blotting, immunofluorescence, and electrophysiological recording |
| Natural Product Pharmacology | Representative dihydroxylated model compound for structure–activity relationship (SAR) studies of flavonoids | Used as a semisynthetic precursor for constructing analog libraries via derivatization reactions—including methylation, glycosylation, and acylation—to support SAR and ADME property evaluation |
Manufacturing Quality Control of 7,8-Dihydroxyflavone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 7,8-dihydroxyflavone by reversed-phase HPLC with UV detection at 254 nm using external standard calibration. |
| Related Substances | HPLC-DAD | Detects and quantifies structurally related impurities (e.g., isomers, degradation products) via gradient HPLC with diode array detection. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals | ICP-MS | Determines total heavy metal content (Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying at 105 C for 2 hours under controlled atmospheric conditions. |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash content by weighing residue after incineration at 600 C for 1 hour. |
| Water Content | Karl Fischer Titration | Determines water content by volumetric or coulometric titration using iodine-based reagent and electrochemical endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light source and standardized cell path length. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in laser light scattering intensity. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic bacteria and molds/yeasts by membrane filtration followed by incubation on selective agar media. |
Technical Specifications of 7,8-Dihydroxyflavone
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 245–249°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7,8-Dihydroxyflavone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7,8-Dihydroxyflavone
Packaging of 7,8-Dihydroxyflavone
Industrial 7,8-Dihydroxyflavone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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