2-Bromo-5-fluoro-3-picoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 38186-85-5 |
| Product name | 2-Bromo-5-fluoro-3-picoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-5-fluoro-3-picoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-5-fluoro-3-picoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-5-fluoro-3-picoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key intermediate in constructing fluorinated pyridine compounds; participates in coupling reactions to prepare targeted drug molecules |
| Pesticides | Intermediate for insecticide and fungicide synthesis | Applied in synthesizing novel fluorinated pyridine-based agrochemicals; introduces active structural units via substitution or coupling reactions |
| Organic Synthesis | Precursor for specialty functional materials | Employed as a heterocyclic scaffold bearing bromo, fluoro, and methyl substituents in synthetic routes toward optoelectronic materials or functional polymers |
Manufacturing Quality Control of 2-Bromo-5-fluoro-3-picoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., isomers, dehalogenated, or oxidation by-products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., dichloromethane, toluene, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-ppt detection sensitivity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (500–600 °C) and weighing of residual non-volatile matter. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral, but used to detect chiral contaminants or degradation). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating; deviation from literature value (68–70 °C) indicates impurity or polymorphic variation. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a standardized suspension (e.g., 1% w/v in water) to detect acidic/basic degradation products or residual catalysts. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution using Mie scattering theory to ensure consistent handling and dissolution behavior. |
| Bulk and Tapped Density | ASTM D6393 | Gravimetric measurement of volume before and after mechanical tapping to assess flowability and compaction characteristics. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur. 5.1.4/USP <61>. |
Technical Specifications of 2-Bromo-5-fluoro-3-picoline
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Refractive Index (n20/D) | 1.530–1.540 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-5-fluoro-3-picoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-5-fluoro-3-picoline
Packaging of 2-Bromo-5-fluoro-3-picoline
Industrial 2-Bromo-5-fluoro-3-picoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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