China Factory Direct
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| CAS number | 38191-34-3 |
| Product name | 2-AMINO-5-BROMOPHENOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural building block for synthesizing antitumor agents (e.g., BRAF inhibitor analogs) and antimicrobial agents | Prepared via diazotization-bromination or selective bromination; commonly used as a starting material for aromatic ring substituent modification |
| Agrochemical Intermediates | Used in synthesizing novel insecticides and fungicides (e.g., triazole derivatives) | Amino group protection followed by bromine-atom participation in coupling reactions (e.g., Suzuki, Heck) to construct heterocyclic agrochemical scaffolds |
| Dyes & Pigments | Key intermediate for synthesizing azo dyes and fluorescent brighteners | Acts as a diazo component coupled with aromatic amines, or undergoes oxidative coupling to form benzoxazole-based fluorescent cores |
| Organic Synthesis | Multifunctional building block enabling highly selective Pd-catalyzed cross-coupling reactions via the C–Br bond | Undergoes Suzuki coupling, Buchwald-Hartwig amination, and related reactions under catalysis by Pd(PPh₃)₄ or Pd(dppf)Cl₂ to construct polysubstituted aromatic amine structures |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., brominated isomers, amino phenol derivatives) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., methanol, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As) after acid digestion by optical emission spectroscopy of plasma-excited atoms/ions. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion of sample with sulfuric acid followed by high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under standardized white light against reference standards. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Loss on Drying | Thermogravimetric Analysis | Quantifies volatile matter (e.g., moisture, residual solvents) by weight loss upon heating at 105 C under controlled atmosphere. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral molecules; confirms absence of racemization or degradation (though compound is achiral, detects chiral impurities). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.