2,6-Dichloronicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 38496-18-3 |
| Product name | 2,6-Dichloronicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,6-Dichloronicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,6-Dichloronicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,6-Dichloronicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing nicotinamide-based herbicides (e.g., nicosulfuron, rimsulfuron) | 2,6-Dichloronicotinic acid undergoes acid chlorination, amination, or esterification, followed by coupling with sulfonylurea structural units to form highly effective, selective herbicides |
| Pharmaceuticals | Structural building block for antiviral and antineoplastic agents | As a chloropyridine carboxylic acid scaffold, participates in condensation, coupling, or substitution reactions to construct the core structure of drug molecules |
| Dyes & Pigments | Intermediate for synthesizing nitrogen-containing heterocyclic dyes | Introduces chromophores via nitration, reduction, and azo coupling reactions for high-performance dye synthesis |
| Organic Synthesis | Functionalized pyridine carboxylic acid derivative used in ligand or catalyst design | Undergoes esterification, amidation, or metal coordination to construct metal–organic frameworks (MOFs) or catalytic systems |
Manufacturing Quality Control of 2,6-Dichloronicotinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~230 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., 2-chloro-6-hydroxynicotinic acid, unreacted 2,6-lutidine) via gradient HPLC-UV or confirmed by mass spectrometry. |
| Residual Solvents (e.g., methanol, toluene, DMF) | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection or mass spectrometric identification, per ICH Q3C guidelines. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES | Multi-element quantification after acid digestion, based on USP <233> or EP 2.4.8, with detection at sub-ppb levels. |
| Chloride Content (Inorganic chloride) | Potentiometric Titration with AgNO₃ | Titration using silver nitrate and a silver/sulfide indicator electrode; measures free Cl⁻ ions from hydrolyzable or ionic chloride impurities. |
| Moisture Content | Karl Fischer Coulometric Titration | Electrochemical determination of water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, indicating crystallinity and presence of eutectic impurities. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Ignition at 700–800 °C followed by weighing of inorganic residue, per USP <281>, reflecting inorganic contaminants and catalyst residues. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Analysis of aerodynamically dispersed powder to determine D10, D50, D90 values, relevant for handling and formulation performance. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 °C using sodium D-line; confirms chiral purity (though 2,6-dichloronicotinic acid is achiral, detects chiral contaminants). |
Technical Specifications of 2,6-Dichloronicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 152–156°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,6-Dichloronicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,6-Dichloronicotinic acid
Packaging of 2,6-Dichloronicotinic acid
Industrial 2,6-Dichloronicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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