4-Methyl-5-imidazolemethanol hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 38585-62-5 |
| Product name | 4-Methyl-5-imidazolemethanol hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-5-imidazolemethanol hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-5-imidazolemethanol hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-5-imidazolemethanol hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate for vitamin B₁ (thiamine) and its derivatives | Used to construct the methylene bridge linking the pyrimidine and thiazole rings |
| Pharmaceutical Industry | Synthesis raw material for famotidine (H₂-receptor antagonist) and other imidazole-based drugs | Introduces the imidazole ring structure via condensation reactions to build the drug molecule backbone |
| Chemical Reagents | Custom synthesis of specialty imidazole derivatives | Serves as a nucleophile or ligand in organic synthesis reactions |
Manufacturing Quality Control of 4-Methyl-5-imidazolemethanol hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Loss on Drying | Gravimetric (105 C drying) | Mass loss measured after drying sample at 105 C to constant weight, reflecting volatile content including residual solvents and water. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantitative analysis of common organic solvents (e.g., methanol, acetone, DMF) per ICH Q3C. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, etc.) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% aqueous solution) | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in a 1% w/v aqueous solution at 25 C using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral molecules in solution; used to confirm stereochemical consistency and detect enantiomeric impurities. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; verifies identity and detects impurities that depress or broaden the melting range. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on stoichiometric reaction between iodine and water in pyridine/methanol buffer. |
| Residue on Ignition | Gravimetric (500-600 C) | Mass of non-volatile inorganic residue after high-temperature ashing; indicates inorganic salt contaminants or catalyst residues. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms using membrane filtration followed by incubation on soybean-casein digest agar or fluid thioglycollate medium. |
Technical Specifications of 4-Methyl-5-imidazolemethanol hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-5-imidazolemethanol hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-5-imidazolemethanol hydrochloride
Safety Information of 4-Methyl-5-imidazolemethanol hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Methyl-5-imidazolemethanol hydrochloride
Industrial 4-Methyl-5-imidazolemethanol hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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