China Factory Direct
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| CAS number | 3879-08-1 |
| Product name | 4-HYDROXYBUTYRIC ACID HYDRAZIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Chemical Synthesis | Used as an organic synthesis intermediate for pharmaceuticals and fine chemicals | Prepared via condensation of 4-hydroxybutyric acid with hydrazide compounds under heating |
| Pharmaceutical R&D | Applied in synthesizing biologically active nitrogen-containing heterocycles or prodrug molecules | Serves as a key intermediate in multistep syntheses, participating in cyclization or functional group transformations |
| Materials Science | Used as a monomer or crosslinker precursor for certain functional polymers | Participates in polymerization or graft modification processes via its hydroxyl and hydrazide groups |
| Biochemical Research | Employed as a probe molecule to study enzyme catalytic mechanisms or protein modifications | Enables labeling analysis through specific reaction of its hydrazide group with carbonyl groups (e.g., Schiff base formation) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, based on peak area comparison against a certified reference standard. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based solvent. |
| Residual Solvents (e.g., Ethanol, Methanol) | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection using internal standard calibration. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metals after acid digestion, based on elemental mass-to-charge ratio detection with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using suppressed conductivity detection after elution with carbonate/bicarbonate buffer. |
| Related Substances | HPLC-UV (Gradient) | Identification and quantification of structurally related impurities (e.g., 4-hydroxybutyric acid, hydrazine, degradation products) using gradient elution and UV detection. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode in a standardized aqueous solution at 25 °C. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content after high-temperature incineration (500–600 °C) and weighing of residual residue. |
| Specific Optical Rotation | [α]D Measurement (Polarimetry) | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at 20 °C using sodium D-line (589 nm). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.