N-Cbz-L-Glutamic acid 5-tert-butyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3886-08-6 |
| Product name | N-Cbz-L-Glutamic acid 5-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Cbz-L-Glutamic acid 5-tert-butyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Cbz-L-Glutamic acid 5-tert-butyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Cbz-L-Glutamic acid 5-tert-butyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of peptide-based drugs | Used for amino acid protection and coupling reactions |
| Medical | Research on biologically active molecules | Applied for introduction of protecting groups in chemical synthesis |
| R&D | Chiral building block for new drug development | Employed in esterification reactions during organic synthesis |
Manufacturing Quality Control of N-Cbz-L-Glutamic acid 5-tert-butyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deprotected forms, isomers) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, DMF, MTBE) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine consumption in a pyridine-free reagent system. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry with isotopic detection. |
| Residual Palladium | ICP-MS | Specifically quantifies Pd from catalytic hydrogenation steps using ICP-MS after microwave-assisted acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified vacuum and temperature conditions. |
| Residual Benzyl Chloride | GC-MS | Detects and quantifies residual benzyl chloride (a potential alkylating agent) using gas chromatography-mass spectrometry with selected ion monitoring. |
Technical Specifications of N-Cbz-L-Glutamic acid 5-tert-butyl ester
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Optical Rotation | -15.0° to -10.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Cbz-L-Glutamic acid 5-tert-butyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Cbz-L-Glutamic acid 5-tert-butyl ester
Safety Information of N-Cbz-L-Glutamic acid 5-tert-butyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Cbz-L-Glutamic acid 5-tert-butyl ester
Industrial N-Cbz-L-Glutamic acid 5-tert-butyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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