Nalidixic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 389-08-2 |
| Product name | Nalidixic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Nalidixic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Nalidixic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Nalidixic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate | Synthesized via alkylation and carboxylation of the quinoline ring; used in the production of first-generation quinolone antibiotics such as nalidixic acid, which inhibits bacterial DNA gyrase |
| Pharmaceuticals | Research-grade antibacterial agent | Used as a reference standard in in vitro antibacterial assays to evaluate susceptibility and pharmacodynamic profiles against Gram-negative bacteria (e.g., Escherichia coli) |
| Chemicals | Organic synthesis intermediate | Serves as a nitrogen-containing heterocyclic precursor in nucleophilic substitution, oxidation, or coupling reactions to construct more complex quinolone derivatives |
Manufacturing Quality Control of Nalidixic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes characteristic absorption peaks of nalidixic acid at specific wavelengths (e.g., 280 nm, 325 nm, etc.) for qualitative identification. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms functional groups in the molecular structure (e.g., carboxyl group, quinolone ring, etc.) by comparing with standard spectra. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 column with a UV detector (approximately 275–325 nm) and a mobile phase such as methanol-water or buffered solution for quantitative analysis of the active ingredient. |
| Ultraviolet Spectrophotometry | Measures absorbance at the maximum absorption wavelength and calculates concentration based on a standard curve; suitable for approximate quantification. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separates degradation products or synthetic intermediates using gradient elution to evaluate purity and impurity limits. |
| Dissolution | Dissolution Test (HPLC or UV detection) | Simulates drug release in a medium using paddle or basket methods; samples are analyzed by HPLC or UV to determine dissolution concentration. |
| Water Content | Karl Fischer Titration | Precisely determines water content in the sample; suitable for quality control of active pharmaceutical ingredients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects heavy metal residues such as lead, cadmium, and mercury to ensure compliance with pharmacopeial limits. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents potentially residual from the manufacturing process (e.g., methanol, ethanol, acetone, etc.). |
| Polymorph Analysis | X-ray Diffraction (XRD) or Differential Scanning Calorimetry (DSC) | Analyzes solid-state polymorphic form to ensure batch-to-batch consistency and prevent polymorphism-related effects on stability and solubility. |
Technical Specifications of Nalidixic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 196-200°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Nalidixic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Nalidixic acid
Packaging of Nalidixic acid
Industrial Nalidixic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply