China Factory Direct
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| CAS number | 389621-78-7 |
| Product name | 4-Aminomethyltetrahydropyran hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antiviral or antitumor candidate compounds | Introduced into active molecular scaffolds via organic synthesis reactions (e.g., amidation, reductive amination) to incorporate the tetrahydropyran moiety |
| Chemical Research | Used as a nitrogen-containing heterocyclic building block for constructing complex molecular architectures | Employed as an amino protecting group or cyclic structural unit in multistep syntheses, followed by deprotection or coupling reactions to yield target compounds |
| Biopharmaceutical R&D | Applied in the development of ligand molecules targeting GPCRs or ion channels | Structurally modified and subjected to target docking screening to optimize pharmacokinetic properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by HPLC separation and UV response relative to main peak. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 700-800 C and weighing residual mass after cooling. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant and silver/silver chloride electrode endpoint detection. |
| pH of Aqueous Solution | pH Meter Measurement | Determines hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode pH meter. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by determining rotation angle of plane-polarized light in solution at specified concentration and wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Organic Volatile Impurities | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, acetone) by gas chromatographic separation and flame ionization detection. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size via scattering pattern analysis of laser beam passing through dispersed sample. |
| Bulk and Tapped Density | Tap Density Tester | Measures mass per unit volume for freely settled (bulk) and mechanically tapped (tapped) powder states. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, in water) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.