China Factory Direct
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| CAS number | 389890-42-0 |
| Product name | (TRANS)-3-AMINOCYCLOBUTANOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate for antiviral drugs (e.g., HCV NS5A inhibitors) | Chiral building block in organic synthesis; incorporated into multistep syntheses to construct complex molecular frameworks |
| Pharmaceutical R&D | Candidate compound development for hepatitis C treatment | Introduced into target molecular structures via acylation, alkylation, or coupling reactions |
| Chemical Research | Chiral auxiliary or ligand precursor | Structural unit used in ligand design for asymmetric catalysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, based on peak area comparison against reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separating enantiomers on a chiral stationary phase and comparing peak areas. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., THF, EtOAc) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Detects trace metal impurities (e.g., Pb, Cd, Ni) by plasma ionization followed by mass spectrometric quantification. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., degradants, isomers) using gradient HPLC with UV detection. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral identity and enantiomeric consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against defined standards under controlled lighting. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 85-89°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +15.0 to +19.0° (c=1, in methanol) |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.