2-Thiopheneacetyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 39098-97-0 |
| Product name | 2-Thiopheneacetyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Thiopheneacetyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Thiopheneacetyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Thiopheneacetyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate for cefalothin sodium | Acylates 7-aminocephalosporanic acid (7-ACA) at the 7-position to introduce the thiopheneacetyl side chain |
| Pharmaceutical Industry | Synthetic intermediate for cefacetrile | Acts as an acylating agent to condense with corresponding cephalosporin nuclei for antibiotic synthesis |
| Pharmaceutical Industry | Synthesis of other thiophene-based antibiotics and derivatives | Serves as a thiopheneacetyl donor for structural modification and synthesis of drug molecules |
| Organic Synthesis | Synthesis of amides and esters | Acts as a highly reactive acylating agent in nucleophilic substitution reactions with amines, alcohols, or phenols |
| Agrochemical Industry | Intermediate for agrochemical synthesis | Used as an acylating agent to synthesize thiophene-containing insecticides or fungicides |
Manufacturing Quality Control of 2-Thiopheneacetyl chloride
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and state of the sample under natural light or standard lighting to determine if it is a colorless to pale yellow liquid, and check for turbidity, precipitation, or suspended matter. |
| Content (Purity) | Gas Chromatography (GC) | Using a capillary gas chromatograph, qualitative analysis is performed based on retention time, and quantitative analysis is conducted using peak area normalization or external standard method to determine the main component content. Suitable for volatile organic compounds. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) or GC-MS | HPLC is used for analysis of non-volatile or thermally unstable impurities; GC-MS enables qualitative and quantitative analysis of unknown impurities, improving detection accuracy. |
| Moisture Content | Karl Fischer Titration | Utilizes the stoichiometric reaction of iodine with sulfur dioxide in methanol with water. Moisture content is determined by potentiometric or coulometric titration to measure trace amounts of water in the sample. |
| Acid Value / Hydrogen Chloride Content | Acid-Base Titration | Dissolve the sample in a suitable solvent (e.g., isopropanol), then titrate free acid (such as HCl) with standardized sodium hydroxide solution to calculate acid value or residual acid content. |
| Infrared Spectral Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Perform infrared scanning of the sample and compare with standard spectra to confirm characteristic molecular structure peaks (e.g., C=O, C–Cl, thiophene ring), used for qualitative identification. |
| Nuclear Magnetic Resonance Analysis | Proton Nuclear Magnetic Resonance (¹H-NMR) | Dissolve the sample in a deuterated solvent and verify compound structure and purity through chemical shift, integration area, and splitting patterns. |
| Boiling Point / Distillation Range | Distillation Method | Determine the boiling point range of the sample under atmospheric or reduced pressure to assess its volatility and compositional consistency. |
| Density | Densimeter or Pycnometer Method | Measure the mass per unit volume at a specified temperature (e.g., 20°C) for physical property control. |
| Refractive Index | Refractometry | Use an Abbe refractometer to measure the refractive index of the sample at a specific temperature, serving as an auxiliary parameter for identification and purity assessment. |
Technical Specifications of 2-Thiopheneacetyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Brown liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Odor | Pungent, characteristic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Thiopheneacetyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Thiopheneacetyl chloride
Packaging of 2-Thiopheneacetyl chloride
Industrial 2-Thiopheneacetyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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