2-BROMOPROPIONIC ACID TERT-BUTYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 39149-80-9 |
| Product name | 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral building blocks for synthesizing chiral drugs (e.g., nonsteroidal anti-inflammatory drugs, β-blockers) | Used as a chiral α-bromo ester in asymmetric alkylation, nucleophilic substitution, or transition-metal-catalyzed cross-coupling reactions (e.g., Pd-catalyzed Stille or Suzuki coupling) |
| Organic Synthesis | Preparation of 2-substituted propionic acid derivatives and chiral propionic acid compounds | Bromine atom displaced via nucleophilic substitution with organolithium or Grignard reagents; C–C bond formation achieved through base-mediated elimination/addition; tert-butyl ester group enables subsequent acidic deprotection |
| Pesticide Development | Synthesis of novel agrochemical active ingredients containing fluorinated or heterocyclic structures | Used as a bromo precursor in cyclization reactions (e.g., condensation with amines to form oxazoline structures) or as an alkylating agent to introduce a propionic acid side chain |
Manufacturing Quality Control of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography (GC) with FID detection | Separation and quantification of impurities by retention time and relative response factors versus main component. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvent residues are vaporized in sealed vials and analyzed via GC-FID or GC-MS for identification and quantification. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Acid Value | Acid-Base Titration (NaOH standard solution) | Neutralization of acidic impurities (e.g., residual 2-bromopropionic acid) with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Halogen Content (Br) | Oxygen Flask Combustion followed by Potentiometric Titration | Sample combusted in oxygen-filled flask to convert organic bromine to bromide ion, then titrated with silver nitrate using silver electrode detection. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | After wet digestion, total heavy metals are quantified by measuring absorbance of ground-state atoms at characteristic wavelength for lead. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Sample ignited at 700-800 C after sulfuric acid treatment; residue weight reflects inorganic impurities. |
| Color | Visual Comparison (APHA Scale) | Comparison of sample solution color against platinum-cobalt standard solutions under controlled lighting conditions. |
| Density | Digital Density Meter (Oscillating U-tube) | Measurement of sample density based on resonant frequency shift of a vibrating U-shaped glass tube filled with sample. |
| Refractive Index | Refractometry (Abbe refractometer) | Determination of refractive index by measuring critical angle of total internal reflection at prism-sample interface. |
| Chiral Purity (if applicable) | Chiral Gas Chromatography (Chiral GC) | Enantioselective separation using chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
Technical Specifications of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.465–1.475 |
| Relative Density (20°C/25°C) | 1.14–1.16 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
Safety Information of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER
Industrial 2-BROMOPROPIONIC ACID TERT-BUTYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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