METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 392338-15-7 |
| Product name | METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing JAK inhibitors (e.g., tofacitinib derivatives) | Critical building block in chiral resolution or asymmetric synthesis routes; incorporated into the drug molecule scaffold via deprotection, coupling, and related steps |
| Pharmaceuticals | Chiral ligand precursor for transition metal-catalyzed asymmetric reactions | Structural basis for nitrogen-containing heterocyclic ligands; participates in C–N bond formation reactions within palladium- and rhodium-catalyzed systems |
Manufacturing Quality Control of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Chiral Purity | Chiral HPLC | Resolves (R)- and (S)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration with iodine-based reagent; based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., THF, toluene, EtOAc) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Detects trace metal impurities (e.g., Pd, Ni, Fe) by plasma ionization and mass spectrometric quantification. |
| Residual BOC Reagent | GC-FID or HPLC-UV | Quantifies residual di-tert-butyl dicarbonate by chromatographic separation and detection relative to calibrated standards. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Residual Palladium | ICP-OES | Measures palladium catalyst residue after microwave digestion, using optical emission from excited atoms in argon plasma. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid or solution against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after controlled heating under vacuum or nitrogen to remove volatile components including moisture and solvents. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular variation in laser light scattering intensity. |
Technical Specifications of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78°C to 82°C |
| Optical Rotation | +24.0° to +26.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
Safety Information of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
Industrial METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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